Mood balance

Pleasure boost / crave

Anhedonia relief −5%

+Social disinhibition

Iron stores +59%

Anemia/Hb +2.7 g/L

Mood: ↓stress/anxiety

Mood: ↓depression, +QOL

Mood: ↓~10%

Mood/anxiety +QOL

Mood/sleep +scores

Mood relief +rapid

Mood: −2.65 HDRS

Mood: relapse −52%

Mood +depression scores

Mood +euphoria/subjective effects

Mood +anxiety/sociality

Stimulant/CV ↑, mood +

Craving/withdrawal ↓, mood +

Lower stress chemistry

Mood symptoms ↓

Aggression/hostility ↓

Anxiety/hostility ↓, 31% norepi

Depression/mood ↓, improved scores

Hb↑ QoL↑

+1–3 g/dL

Transfusions↓ 20%

Depression relief +2.65

Mania relief 100%

Lower relapse 0.33

Mood/anxiety ↓

Stress/cortisol ↓

Depression ↓

Lower TRP, worse mood

Higher TRP, better mood

Depression ↓, side effects ↓

+20% responders, fewer AEs

Mood: depression↓

Anxiety/irritability↓ +10%

Cognition/wellbeing↑ +30%

Depression↓ 10-20%

Anxiety/aggression↓ ~5-10%

TRP↓ mood↓

TRP↑ mood↑

Phe/DA shifts, worse mood

Phe↑ 77%; PRL↑, DA↓

Phe↓ 39%; mood↑

Mood+sleep ↓, +PSQI

Circadian advance ~2h, mood ↑

Mood balance: ↑anxiety/depression

Mood balance: −PMS symptoms

Mood balance: +mental well-being

Depression/anxiety ↓

Mood/alertness ↑

Depression↓ 4-55%

Anxiety/stress↓ modestly

Mood balance↑

Alertness↑ mood

Fatigue↓ irritability↓

GSH↑, mood↑

Oxidative stress↓, mood↑

Mood ↑ stress/depression

Mood ↑ +10.44

Anxiety ↓ ~5-8

Depression/mood ↓

Mood ↓ homocysteine

Mood ↑ 52%

Mood ↓ anxiety/depression

Psychological mood +

Hair response +12.5%

Mood↑ anxiety↓

Depression↓ +20.4%

Stress/anxiety↓

Less anxiety/stress

Mood +12.6

Anxiety ↑/↓ balance

Mood uplift +7.0

Psychosis/anxiety shift

Mood: depression↓

Mood: anhedonia↓

Mood: fatigue↓

Mood ↓, stress ↓

Mood ↓, anxiety ↓

Mood symptoms ↓

Stress/anxiety ↓

Depression down; response faster

PMS/anxiety down; mood up

Mood/behavior ↓

Caregiver distress ↓

Anxiety/depression ↓

Agitation/crying ↓

Sleep/mood ↑

Mood uplift 4.6 pts

Anxiety/stress down 2.4

Depression ↓

Mood/anxiety ↓

Fatigue ↓

Mood ↑, anxiety ↓

Anhedonia ↓, confidence ↑

Depression ↓; remiss. +18.5pp

Mood stable; biomarkers ↑500%

Male benefit d=0.95

Mood↓; anhedonia↑ AMPT

Mood↑; anxiety↓ L-dopa

Mood: ↓ depressive/anxiety

Mood: ↓ craving/irritability

+80% response

Mood↑ DHEA 50mg

Depression↓ 60%

Anxiety↓ DHEA

Mood balance: lower symptoms

Mood balance: +4 HDRS / 34% tHcy

Mood balance: less relapse

Depression severity, response/remission

-18.5pp response; +14.1pp remission

Earlier mood improvement

Anxiety ↓; cortisol flat

Mood balance ↑ anxiety ↓

Mood up, anxiety down

THC euphoria +, withdrawal -

Positive mood/elfeeling +

Depression up 4.6

Schizophrenia symptoms down

Ketamine: mood ↓14

Ketamine: rapid response

Metabolic/plasticity mood lift

Mood: +

Anxiety/stress: −

Lower anxiety/stress

Mood lift +56%

Less stress markers

Stress/anxiety ↓

Mood/cognition ↓ fatigue

Mood ↑ serine/DCS

Depression −4.4 / −34%

Neg symptoms −30%

Mood/QoL ↑ +

Hypothyroid/mood ↓

Mood ↓; anxiety ↓

Depression ↓ ~10 pts

Well-being ↑; stress ↓

Stress/mood ↓ ~3

Depression/anxiety ↓

Fatigue/attention ↓

Depression ↓; QoL ↑

Craving/anhedonia ↓; mood ↑

Mood ↑ butyrate

Mood ↓ fatigue

Improved mood, -17 GDS

AA/EPA shift, mood boost

Mood↓ apathy/distress

Mood↓ depression/anxiety/apathy

Mood/stress ↓, +4.3

Fatigue/anxiety ↓, +2.2 g/dL

Better mood/stress

+QoL mood

Anxiety ↓; +20% remission

Mood/attention ↑

Safety unchanged

Mood ↓, +5-7

Sleep/anxiety ↑, −3.1

Mood ↓ BPSD/apathy

Mood ↑ stress relief

Mood better, impulsivity lower

Anxiety/migraine improved

Postpartum depression lower

Mood boost; +26% remission

Brain energy/connectivity; symptom relief

Mood/QoL ↑

Anxiety −

PANSS total −6

Stress/fatigue ↓

Mood/anhedonia ↑

Mood better + faster

Depression/cognition +1 MMSE

Mood symptoms -32%

Depression faster -1.9

Anxiety, stress ↓

Sleep, wellbeing ↑

Mood/fatigue + stress

PMS/cortisol + distress

Anxiety/stress down; -7.5

Attention/fatigue up; p<0.05

Mood↑, anxiety↓

HDRS −5.1; TAC↑

EPDS↓

Mood balance: better depression

Mood balance: less mania

Lower cortisol, better mood

Sleep/glucose, better morning mood

Mood ↑, RT +0.37

Depression/anxiety ↓, +3.7/-3.1

Cortisol ↓, mood↑

Depression/anxiety: +improved

Mood balance: improved

Mood↓ apathy/distress

Mood↓ anxiety/stress

Stress hormones ↑, anxiety ↓

Psych symptoms ↓, platelets ↓

Anxiety/mood ↓

Sleep quality ↑

Cognitive boost, +NGF

Mood arousal, dislike +

Calmer mood, -4 to -6

Stress/anxiety down, ~-4 to -6

Mood: ↓ depression

Mood: mixed; ↑ anxiety

Hot flashes down

Mood +10%

Anxiety improved

Pain/anxiety ↓

Delirium −11.2%

Anxiety/depression ↓ ~77-81%

Hot flashes/QoL: mixed

Mood symptoms ↓

Depression/anxiety ↓

Cortisol ↓; T4 no change

Menopause symptoms/QoL improved

PMS symptoms/social QoL improved

Mood ↓ depression

Mood ↓ panic/OCD

Mood ↑; depression/anxiety

+ significant

Fatigue/depression ↓; mood ↑

Anxiety/fatigue relief 79%

Headache reduction

Fatigue down 30–50%

Improved mood, DLQI −5.9

Better life impact, +36%

Skin benefit, GI AEs

Craving/anxiety ↓

BPRS ↓ (P=0.004)

Appetite/weight ↑

Mood/sleep ↑

Fatigue -28%; mood +39%

Anxiety/depression improved

Severity -16%

Mood+1.97 / ↓internalizing

Mania −14.6; lethargy

Memory up

Cognition up

Hepatic mood/QoL +23.7

Stress/sleep mood lift

Mood stability −27.5%

Depression prevented +4.69

Stress biomarker −56.1

Mood improvement -10.36

Anxiety/psyche relief

Mood symptoms reduced

Depression scores down

Stress/anxiety ↓ -9.4

Depression/anxiety ↓ +serotonin

Calmness up; EEG +

Depression scores down, faster

Vitality/general health up

Mood ↓; craving ↓

Depression improved

Remission +p=0.045

Mood↓, no cognition

Mood↓; +response/remission

Mood↓; -8.86 Y-BOCS

Mood better: -2.69

Anxiety/depression down

Psychological score down

Mood relief, -

Anxiety/PTSD ↓

Memory/attention ↑

Mood ↑ 65%

Mood ↑ modestly

Faster response, +27% responders

Self-report mood/anxiety gains, CGI flat

Depression eased (-4 to -6)

Alcohol unchanged

Sleep/anxiety improved

Depressed mood reduced

Mood balance↑ response

Mood balance↑ ESR/Hb

Mood symptoms ↓ 41-51%

Blues incidence ↓16.4%

Depression/anxiety ↓

PHQ-9 −2.78; GAD-7 −2.35

Psych symptoms −3.44

Mood balance improved

Mood +4.2, anxiety

Functioning +4.5

Depression/anxiety −4.2/−2.5

Functioning +4.5

PMS mood relief −11.75

Placebo minimal change −1.20

Mood balance +?

Cognition +?

Mood lift −45%

Biomarkers unchanged

EPDS prevalence ↓9.6%

ALA levels → lower distress

Anxiety/stress down

Cortisol changes (males)

Depression/anxiety ↓ −4.14

HADS depression/anxiety ↓

Comfort up; pain unchanged

No pain change

Burnout↓ mood scores

Depression↓ vs placebo

Obsessive/phobic mood ↓

-1.00,-0.98

Thiamine-linked depression ↓

Glucose↓ ~13% mood↑

Depression/anxiety/stress↓

Better mood/energy (+19%)

Symptom relief, modest mood

Survival, appetite, sleep

T3↑, T4↓

Symptom/QoL: subset↑

Anxiety↓, memory↑

Depression↓, anxiety↓

QoL, cognition +

Memory +

Faster reaction, better vigor

Executive function gains

Lower negative mood, +vigor

No fatigue change

Antioxidants up; mood support

BDNF/IGF-1 up, cognition +

Symptom relief -66%

Hormones unchanged

ADHD symptoms -34%

Hyperactivity -34%

Mood better, hormones unchanged

+1.6 IIEF, mood up

Anxiety/sleep improved

Greene score -12m

Executive + biomarker benefit

Responder cognition +2.12 MMSE

Stress ↓ -5.9

Sleep/alertness ↑

Startle down, mood steadier

Working memory, mood up

Mood improves; no difference

Brain-age lower, symptoms better

Hot flushes/palpitations ↓

Kupperman Index ↓

Calming: BP down

Relaxation: breathing -

Energy/sleep up

Stress/fatigue down

Autonomic distress ↓

H% +9.4%

Mood lifts, -p<0.05

Oxygenation up, mood better

Mood balance: similar benefit

AEs +18.5%

Anxiety down, mood steadier

Cognition up, mood supported