Mangosteen

10 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Moderate

Systemic inflammation ↓ CRP

Local gingival inflammation ↓ IL-1β/PGE2/MMP-8

357 people

Moderate

Gum inflammation↓

Pocket depth↓

318 people

Moderate

Weight/waist −5kg

Glucose/lipids ↓

215 people

Weight management

Moderate

Weight −5kg

Waist −12cm

215 people

Weak

Weight/waist −5.2 kg

Lipids improved; TG −42%

155 people

Skin appearance

Weak

Smoother texture, +1 mm³

Less acne, better tolerance

137 people

Weak

Density + ATP rise

MDA near-normal

154 people

Weak

Depression/anxiety −4.2/−2.5

Functioning +4.5

152 people

Weak

CRP down; CD4 up

IL-1α/β up

59 people

Exercise recovery

Weak

Strength/endurance +48%

+6.6 reps

38 people

Main Effects

Systemic inflammation ↓ CRP

Local gingival inflammation ↓ IL-1β/PGE2/MMP-8

Moderate

357

Gum inflammation↓

Pocket depth↓

Moderate

318

Weight/waist −5kg

Glucose/lipids ↓

Moderate

215

Weight management

Weight −5kg

Waist −12cm

Moderate

215

Weight/waist −5.2 kg

Lipids improved; TG −42%

Weak

155

Skin appearance

Smoother texture, +1 mm³

Less acne, better tolerance

Weak

137

Density + ATP rise

MDA near-normal

Weak

154

Depression/anxiety −4.2/−2.5

Functioning +4.5

Weak

152

CRP down; CD4 up

IL-1α/β up

Weak

59

Exercise recovery

Strength/endurance +48%

+6.6 reps

Weak

38