L-Methionine

Choline depletion ↑ALT

Homocysteine ↓ with supplements

ALT/cholestasis ↓

Fibrosis risk ↓

Liver prediction +0.06

GSH/Cysteine detoxification

Homocysteine lowering

Lipids ↑ with methionine

Homocysteine ↑; vessel function ↓

Methionine restriction: fat loss

Muscle protein synthesis +

Growth + weight gain

Amino acids + methionine

Glutathione↑, MDA↓

Selenium/antioxidants↑

Homocysteine↓, risk↓

Methylation↑, aging↓

Memory/executive +0.84

+ methylation/choline

Depression response +18.5%

Depression ↓; remiss. +18.5pp

Mood stable; biomarkers ↑500%

Male benefit d=0.95

Leukocyte/antibody boosts

−55% anti‑TPO

−34pp mucositis

Met boost; AA markers

Cys spares Met need

Immune ↓; TgAb −

Inflammation ↓; Steroidogenesis ↑

Digestive diges.+VFA

Symptoms/ulcer relapse

Mucositis -24%

Pain relief similar vs NSAIDs

Tenderness down; liver enzymes +

Methionine: DMI, milk, protein

Fatigue: cycling +1.4 min

Faster healing, fewer relapses

Lesion scores down

Ulcer healing +23pp

Hair outcomes +1.01

Wool traits, methionine