GABA

Anxiety↓ stress†

Sleep/attention↓ anxiety

Cortisol/HR↓ stress

Pain/sleep gains

+50%

Mood/wellbeing gains

Sleep improved; pain eased

Sleep worsened; sedation rose

Relaxation: sleep/anxiety +72%

Relaxation: pain/spasticity ↓

Relaxation: sedation/memory ↓

Sedation/memory worsened

Sleep onset shortened

Mood/anxiety +QOL

Mood/sleep +scores

Mood relief +rapid

Attention/memory gains

+6 to +10%

Attention faster, steadier

Pain/opioid use ↓

Mobility/recovery ↑