Saffron

Depression↓ 4-55%

Anxiety/stress↓ modestly

Mood balance↑

Lower inflammation

Boosts immune regulation

Stress/anxiety ↓ p<0.04

Depression/anxiety ↓ p<0.001

Mood/depression ↓

Inflammation/health ↓

Lipids↓ TG/LDL

Blood sugar↓ FBG/HbA1c

BP/inflammation↓

Antioxidants +TAC

Oxidative stress -MDA

Inflammation ↓ hs-CRP

Sleep/melatonin ↑

Stress/anxiety ↓

Depression scores ↓

Weight ↓, glucose/lipids

Weight ↓, appetite↓

Cognition +0.8

Dementia severity

Stroke recovery

Better sleep quality

+25 min TIB

Improved sleep efficiency

Cognition +0.78

Dementia severity better

ADHD/OCD similar

Vision/function +0.69 letters

Retinal function/IOP -3.25 mmHg

Erectile function +77%

Female sexual function

FSFI +8.3 points

Pain/inflammation ↓

Tender joints −1.38

Treg/miRNA shifts

Colitis severity -0.83

Dyspepsia symptoms +78%

Fatigue scores down

Physical/cognitive fatigue down

Weight loss, snacking ↓

Greater weight loss; fewer snacks

PMS symptoms ↓

Mood symptoms ↓