Sarcosine

Depression up 4.6

Schizophrenia symptoms down

Brain markers + symptoms

Depression benefit +19%

Schizophrenia symptoms −19%

Psychosis relief +19%

Mood/cognition gains -4.6

Motivation/confidence ↑

Motivation/confidence ↑

Cognition/attention +?

Symptoms -19%

Sharper cognition/negative symptoms

~19-30% better

Global psychiatric gains

Symptoms + function

+ cognition/function

Cognition/symptoms +p<0.05

Global function +p<0.05

PANSS/SANS better

HAM-D/remission better

Depression, remission +

Early mood +