Proof.Fit

Vitamin B9

14 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Homocysteine ↓, cardiac risk

Vascular function ↑, Hcy ↓

528,161 people

Pregnancy support: NTD/birthweight↓

Counseling: folate use↑ +26.5pp

336,594 people

Folate status↑, Hcy↓

Anemia/toxicity↓, Hb↑

125,429 people

Cognition + homocysteine

~30% tHcy drop

Brain atrophy −40%

933,820 people

Lower liver/blood toxicity

Higher folate biomarker levels

Better cancer control

99,634 people

Mood: −2.65 HDRS

Mood: relapse −52%

869,827 people

Hb↑, fatigue↓

Anaemia↓, Hb↑

53,924 people

Brain/cognition protection

Homocysteine↓, folate↑

53,587 people

Processing speed +8.8

Memory/attention + small gains

12,721 people

Nerve symptoms, homocysteine

+30% homocysteine drop

Nerve conduction improves

25,542 people

Arsenic detox: +DMAs -InAs

Homocysteine detox: -30%

Liver enzymes: -0.6 IU/L

10,686 people

Fewer infections, shorter illness

Lower inflammation, better immunity

8,459 people

↓ Insulin/hunger peak

+1.7 appetite score

↑ reported appetite/energy

161 people

Hemoglobin ↑

Memory/attention ↑

129 people