Folic Acid

Hcy↓ +31%

FMD/AIx↑

Knowledge+uptake +26.5pp

Defects −47% / −36%

Hb/folate +10%

Lower homocysteine

Better vessel function

Lower stroke risk

Homocysteine ↓32%

Betaine ↑38%

Folate↑, Hcy↓

Hb/iron status↑

Liver toxicity, discontinuation

DNA damage, apoptosis

Homocysteine↓; folate↑

Stroke/cognition/flow↑

Memory/cognition +

Homocysteine ↓

Depression relief +2.65

Mania relief 100%

Lower relapse 0.33

Folate ↑; wellbeing +

Wellbeing +10%; mood

Sleep ↑; wellbeing +

Sperm quality +47%

Pregnancy +18.9%

Folate intake +60%

Folate/B12 better clarity

Omega-3 boosts folate

Hb ↑, fatigue ↓

Iron status ↑, fatigue ↓

Recovery improved; +31%

Toxicity reduced; -21 pp

Immune/infection ↓, +5‑fold folate

Inflammation ↓, homocysteine −22%

Neutropenia ↓, WBC +