Proof.Fit

Choline

18 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Cognition +3.5%

Memory/behavior +25%

8,709 people

Liver/DNA damage

Respiratory survival

8,006 people
Memory
Strong

Memory +25%

Cognition/behavior +3.5%

Choline → choline boost

5,956 people

Cognition + memory

+3.5 / +13.9%

Behavior + function

5,328 people

Methylation/homocysteine: -29%

Fatty liver/oxidation

5,743 people

Pregnancy choline↑, carnitine↓

Placental/fetal markers shifted

3,265 people
Learning
Strong

Memory + learning

Attention + processing

3,739 people

Choline boost, memory +25%

Visual/brain function, IOP -7 mmHg

2,408 people

Memory + cognition

Attention + EEG

-3.2 ADAS-cog

2,723 people

Memory/attention +

EEG gating/immediate focus

+

2,270 people
Fat burn
Strong

↓ liver fat, +fat ox

↓ carnitine, +ketones

3,589 people

TMAO↑/↓ heart risk

Lipids, BP, restenosis ↓

2,393 people

Liver fat↓, ALT↓

Fibrosis↓, steatosis↓

1,874 people

Muscle strength +10%

Muscle loss -1kg

724 people
Mood balance
Moderate

Mood↓ apathy/distress

Mood↓ depression/anxiety/apathy

604 people

Gut inflammation ↓

TMAO ↑/↓ 250%

484 people

Stress resilience: HRV/BP +14%

Stress resilience: fetal cortisol -33%

221 people

Fatigue improved +14%

Energy/autonomic +10%

95 people