proof.fit

Choline

18 benefits mapped to clinical evidence across supplements.

Serves the goals:CardiovascularCognitionDetoxEnergyEssential Health

Benefit Evidence

Brain health
Strong

Cognition +3.5%

Memory/behavior +25%

8,709 people
Cell health
Strong

Liver/DNA damage

Respiratory survival

8,006 people
Memory
Strong

Memory +25%

Cognition/behavior +3.5%

Choline → choline boost

5,956 people
Healthy aging
Strong

Cognition + memory

+3.5 / +13.9%

Behavior + function

5,328 people
Metabolism
Strong

Methylation/homocysteine: -29%

Fatty liver/oxidation

5,743 people
Pregnancy support
Strong

Pregnancy choline↑, carnitine↓

Placental/fetal markers shifted

3,265 people
Learning
Strong

Memory + learning

Attention + processing

3,739 people
Nerve health
Strong

Choline boost, memory +25%

Visual/brain function, IOP -7 mmHg

2,408 people
Mental clarity
Strong

Memory + cognition

Attention + EEG

-3.2 ADAS-cog

2,723 people
Focus & concentration
Strong

Memory/attention +

EEG gating/immediate focus

+

2,270 people
Fat burn
Strong

↓ liver fat, +fat ox

↓ carnitine, +ketones

3,589 people
Heart health
Strong

TMAO↑/↓ heart risk

Lipids, BP, restenosis ↓

2,393 people
Liver support
Moderate

Liver fat↓, ALT↓

Fibrosis↓, steatosis↓

1,874 people
Muscle maintenance
Moderate

Muscle strength +10%

Muscle loss -1kg

724 people
Mood balance
Moderate

Mood↓ apathy/distress

Mood↓ depression/anxiety/apathy

604 people
Digestive support
Moderate

Gut inflammation ↓

TMAO ↑/↓ 250%

484 people
Stress resilience
Moderate

Stress resilience: HRV/BP +14%

Stress resilience: fetal cortisol -33%

221 people
Energy & Fatigue
Weak

Fatigue improved +14%

Energy/autonomic +10%

95 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Thiamine

Shares 13 benefits: brain health, digestive support, energy & fatigue, focus & concentration

L-Serine

Shares 13 benefits: brain health, cell health, energy & fatigue, focus & concentration

Riboflavin

Shares 12 benefits: brain health, cell health, energy & fatigue, focus & concentration

Phosphatidylcholine

Shares 12 benefits: brain health, cell health, digestive support, energy & fatigue

Niacin

Shares 11 benefits: brain health, cell health, digestive support, energy & fatigue

Acetyl-L-Carnitine

Shares 10 benefits: energy & fatigue, focus & concentration, healthy aging, heart health

Products with Choline

Search all

183 products whose verified label declares Choline — not every bottle that mentions it in a title.

Stonehenge Health

Stonehenge Health Dynamic Brain

Vitamin A 180 mcg RAE · Vitamin C 90 mg · Vitamin D3 4 mcg +38 more

$58.00Bacopa Monnieri

NOW Foods

NOW Foods Supplements, Vitamin B-100, Energy Production*, Nervous

Thiamine 100 mg · Riboflavin 100 mg · Niacin 100 mg +8 more

$13.02Diet & Sports Nutrition

Optimum Nutrition

Optimum Nutrition Serious Mass Weight Gainer Protein Powder

Vitamin A 750 mcg · Vitamin C 60 mg · Vitamin D 5 mcg +26 more

$61.94Weight Gainers

Pure Encapsulations

Pure Encapsulations DIM Detox, 60 Capsules

BioResponse DIM Diindolylmethane Complex 100 mg · Starch 0 NP · Diindolylmethane 0 NP +13 more

$58.00DIM Supplements

Dr. Berg Nutritionals

Dr. Berg Liver Cleanse Detox Capsules w/Unique Blend of Milk Thistle

Folate 260 mcg DFE · Choline 100 mg · Proprietary Blend 537 mg +7 more

$23.99Milk Thistle

Kyolic

Kyolic Aged Garlic Extract Cholesterol Health* Formula 104

Aged Garlic extract powder 600 mg · Lecithin 380 mg

$31.99Garlic

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.

Pilot Study of Prenatal Choline SupplementationCholine · Brain Development, Choline Nutrition · 50 participants planned · ClinicalTrials.govRecruitingMaternal Intake of Eggs and Infant NeurodevelopmentCholine · Pregnancy Related · 100 participants planned · ClinicalTrials.govRecruitingNutrition to Support Postoperative RecoveryCholine · Postoperative Care, Postoperative Complications, Cognition · 100 participants planned · ClinicalTrials.govRecruiting