Proof.Fit

Theobromine

12 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Flow/oxygenation +

Walking/healing +

2,311 people
Endurance
Moderate

Walking +30-400%

LVEF +12%

Soreness/reaction improved

1,209 people
Hydration
Moderate

Renal protein loss −81%

Kidney function preserved

721 people
Metabolism
Moderate

Lipids/waist improved

NASH histology/enzymes improved

452 people

Cocoa: better alertness

Pentoxifylline: modest cognition

545 people
Mood balance
Moderate

Cognitive boost, +NGF

Mood arousal, dislike +

310 people
Alertness
Moderate

Improved alertness, cognition

-21→107 ml/min

226 people

Alertness + performance

Fatigue/energy boost

216 people

Less cough; +35% oxygenation

Less airway narrowing; shorter ICU

139 people

Antioxidant +4-8%

Inflammation -75%

106 people

Liking + reinforcement

Mental performance + health

184 people

Slow caffeine clearance

Improved attention/performance

+31 h half-life

162 people