Proof.Fit

Theobromine

12 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Main Effects
Blood circulation

Flow/oxygenation +

Walking/healing +

Strong
2,311
Endurance

Walking +30-400%

LVEF +12%

Soreness/reaction improved

Moderate
1,209
Hydration

Renal protein loss −81%

Kidney function preserved

Moderate
721
Metabolism

Lipids/waist improved

NASH histology/enzymes improved

Moderate
452
Mental clarity

Cocoa: better alertness

Pentoxifylline: modest cognition

Moderate
545
Mood balance

Cognitive boost, +NGF

Mood arousal, dislike +

Moderate
310
Alertness

Improved alertness, cognition

-21→107 ml/min

Moderate
226
Energy & Fatigue

Alertness + performance

Fatigue/energy boost

Moderate
216
Respiratory comfort

Less cough; +35% oxygenation

Less airway narrowing; shorter ICU

Weak
139
Antioxidant

Antioxidant +4-8%

Inflammation -75%

Weak
106
Motivation & confidence

Liking + reinforcement

Mental performance + health

Weak
184
Focus & concentration

Slow caffeine clearance

Improved attention/performance

+31 h half-life

Weak
162