Proof.Fit

Erythropoiesis-Stimulating Agents

11 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Hb↑/transfusions↓

Iron markers↑

185,236 people

Fatigue↓ Hb↑

Energy↑ Hb↑

93,136 people
Wellbeing
Strong

Hb↑, QoL↑

Transfusions↓, fatigue↓

68,699 people
Endurance
Strong

Hb maintained

+1.3 g/dL

Transfusion reduced -83%

66,557 people

Hb stable/↑ ~1–2 g/dL

Less transfusion/ESA use

51,521 people

Hb stable

+1.3 g/dL

Respiratory comfort unknown

23,294 people

Hb↑, transfusions↓

+1.3 g/dL

Iron stores↑, Hb↑

25,574 people

Hb↑ + recovery

Iron stores↑ + faster

18,514 people

Hb↑ QoL↑

+1–3 g/dL

Transfusions↓ 20%

17,689 people

Hb/iron ↑, fatigue/QOL

Neuro/cognition +8-13 pts

8,900 people

RLS symptoms −8 to −13

Sleep better, less meds

1,078 people