Evening Primrose Oil

Hydration up, TEWL down

+8.9 CORN units

Dryness symptoms improved

Hot flashes/sweating ↓

Irritability, CRP ↓

Hot flash severity -42%

Anti-inflammatory shift

DAS28 -1.08

IL-6 -69%

Disability & relapse ↓

Pain & symptoms ↓

Barrier + hydration

DGLA / symptoms

Immune markers improved

EDSS better, PUFAs

DAS28 −1.0, pain

Morning stiffness only

Barrier + hydration

Itch/AD severity +96%

Psych symptoms −3.44

Mood balance improved

Dryness/comfort improved

Tear meniscus height increased