Evening Primrose Oil

10 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Moderate

Hydration up, TEWL down

+8.9 CORN units

Dryness symptoms improved

216 people

Hormone balance

Moderate

Hot flashes/sweating ↓

Irritability, CRP ↓

Hot flash severity -42%

277 people

Moderate

Anti-inflammatory shift

DAS28 -1.08

IL-6 -69%

203 people

Moderate

Disability & relapse ↓

Pain & symptoms ↓

196 people

Weak

Barrier + hydration

DGLA / symptoms

140 people

Weak

Immune markers improved

EDSS better, PUFAs

165 people

Weak

DAS28 −1.0, pain

Morning stiffness only

100 people

Weak

Barrier + hydration

Itch/AD severity +96%

90 people

Weak

Psych symptoms −3.44

Mood balance improved

189 people

Weak

Dryness/comfort improved

Tear meniscus height increased

76 people

Main Effects

Hydration up, TEWL down

+8.9 CORN units

Dryness symptoms improved

Moderate

216

Hormone balance

Hot flashes/sweating ↓

Irritability, CRP ↓

Hot flash severity -42%

Moderate

277

Anti-inflammatory shift

DAS28 -1.08

IL-6 -69%

Moderate

203

Disability & relapse ↓

Pain & symptoms ↓

Moderate

196

Barrier + hydration

DGLA / symptoms

Weak

140

Immune markers improved

EDSS better, PUFAs

Weak

165

DAS28 −1.0, pain

Morning stiffness only

Weak

100

Barrier + hydration

Itch/AD severity +96%

Weak

90

Psych symptoms −3.44

Mood balance improved

Weak

189

Dryness/comfort improved

Tear meniscus height increased

Weak

76