Proof.Fit

Vitamin B6

17 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Metabolism
Strong

Homocysteine↓, B6↑

Folate/methylation↑, homocysteine↓

41,074 people
Heart health
Strong

Lower TMAO/homocysteine

Better vessel function

Fewer MI/stroke

23,424 people
Pregnancy support
Strong

Nausea relief

Birth weight +10%

Blood pressure -38%

7,958 people
Nerve health
Strong

Neuropathy symptoms↓

Movement/tremor relief

2,861 people
Mood balance
Strong

Mood ↓ homocysteine

Mood ↑ 52%

Mood ↓ anxiety/depression

5,384 people
Mental clarity
Strong

Memory/cognition +hcy

Brain atrophy −30%

2,718 people
Vitality
Moderate

Liver enzymes/fatty liver -42%

B6/PLP, performance/weight

1,033 people
Eye health
Moderate

AMD risk ↓34%

Cataract odds ↓

18,378 people
Nutrition source
Moderate

B-vitamin status ↑

Homocysteine ↓ / ω-3 ↑

Hemoglobin & cognition ↑

1,389 people
Stress resilience
Moderate

Stress/anxiety ↓

-3 points

1,309 people
Focus & concentration
Moderate

Better attention/memory

Reduced cognitive decline

781 people
Blood sugar
Moderate

Blood sugar ↓

HbA1c/FPG ↓

516 people
Immune support
Moderate

Immune cells up

Viral reactivation down

CD4+ 60%→37.5%

532 people
Skin health
Moderate

PPE/HFS ↓ incidence

QoL/pain improved

215 people
Sleep quality
Moderate

Less waking, better sleep

PSQI −44%, better sleep

Improved sleep with lithium

175 people
Energy & Fatigue
Weak

Better endurance +26%

Lower performance -11.6%

445 people
Menstrual comfort
Weak

PMS symptoms -45%

Broad micronutrients, remission 72%

198 people