Proof.Fit

Docosahexaenoic Acid

20 benefits mapped to clinical evidence across supplements.

Benefit Evidence

TG↓, LDL↑

O3I↑, TG↓

HDL↑, LDL↑

46,973 people

Triglycerides, BP -5 mmHg

AF recurrence 38.5% vs 77.5%

Vascular function, plaque slower

71,440 people

DHA status growth +

vision/neurodevelopment +

30,355 people

Inflammation↓ CRP/IL-6

Inflammation↓ TNF-α/IL-6

Inflammation↓ CRP -15%

12,654 people

AMD risk ↓

Visual acuity ↑

56,862 people

Brain networks +0.015

+4 IQ / +7 MDI

Memory/attention + DHA

18,779 people

Lower inflammation, more n‑3

Immune function shifts

12,766 people
Memory
Strong

Memory +0.2

Memory +7

Memory +3.5

11,697 people

Improved dilation, flow

+31%, -26%

Lower constriction, clotting

7,492 people

Cardio-protection, −10% events

Brain/aging support, cognition

6,890 people

Depression↓ 10-20%

Anxiety/aggression↓ ~5-10%

4,340 people

Focused attention + faster processing

+3.5 IQ, -6.9 BPD

Better attention, memory

5,650 people

BP ↓ 3-6 mmHg

DHA stronger ↓ BP

SBP/DBP ↓, HR ↓

3,411 people

↓NE, stress

↓anxiety/cortisol

↑HRV, ↓MAP

1,630 people

Steatosis −53%, ALT

Triglycerides, insulin sensitivity

Liver enzymes ↓

1,349 people

Joint comfort +RA

Pain/stiffness −5 to −10

1,179 people

fatigue ↓, +74%

physical function ↑, +11%

839 people

Duration↓wakings↑58min

Efficiency↑latency↓1.7pp

PSQI↑cortisol↓

1,376 people
Bone health
Moderate

↑n-3, ↓resorption

↑Ca retention, ↑BMD

180 people

Hydration indirect, severity −11.2

Inflammatory shift, >10-fold

83 people