Proof.Fit

Phosphatidylcholine

17 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Main Effects
Heart health

Lipid lowering, HDL↑

Plaque/heart risk ↓

Strong
8,547
Fat burn

Higher choline: less fat

Omega‑3 lipids: less fat

Strong
3,066
Brain health

Cognition +5–15%

Brain lipids/choline ↑

Attention/memory +

Strong
3,055
Cell health

Choline deficiency: −30% PC

Liver fat improved +13.8

DHA/EPA enrichment: +4.7%

Strong
2,406
Memory

Memory/cognition +MMSE

Behavior/ADL decline -

Strong
2,680
Cholesterol

HDL/efflux ↑

LDL/TG ↓

Strong
1,463
Focus & concentration

Improved memory/attention

Better cognition, 12.2%

Faster processing, +13.0

Strong
1,968
Liver support

Liver enzymes/steatosis ↓

Choline/PC status ↑

Strong
1,806
Digestive support

Digestive support improved

GI protection + recovery

IBD symptom reduction

Moderate
1,013
Nerve health

Cognitive decline ↓

Behavioral symptoms ↓

Dementia conversion ↓8.2%

Moderate
1,133
Healthy aging

Memory/choline +3.35

Dementia risk ↓ 18%

Vaccine antibody +30.4pp

Moderate
5,929
Mood balance

Mood ↓ BPSD/apathy

Mood ↑ stress relief

Moderate
680
Eye health

Visual function + stabilisation

Lutein/zeaxanthin +

Moderate
637
Exercise recovery

Choline/PC recovery +

Recovery markers −

Moderate
248
Detoxification

Choline→TMAO shift

−30% choline, +484% TMAO

Choline/PC detox handling

Moderate
222
Skin hydration

↓Hydration, ↑TEWL

-

Moderate
215
Energy & Fatigue

Mitochondria + OXPHOS

Phospholipids, PC:PE↓

Weak
35