Proof.Fit

Arachidonic Acid

19 benefits mapped to clinical evidence across supplements.

Benefit Evidence

AA↔EPA/DHA shift

Cell defense/function +20%

Oxidative stress ↓

22,895 people

↓AA eicosanoids

↓platelet aggregation

↑EPA/AA ratio

14,565 people

↓AA-platelets

↑EPA/AA,↓TxB2

11,903 people

AA/DHA boosts brain growth

+7 MDI; visual gains

AA/DHA balance matters

9,880 people

AA↓/EPA↑ lipids

TG↓ HDL↑

27,579 people

Lower LTB4/LTE4

AA→EPA/DHA shift

Immune support +14%

5,608 people

Eye health: better vision

ROP ↓ 16-17%

4,232 people
Memory
Strong

Brain/vision, +7

Memory/attention, +5.4

3,732 people

vasospasm/infarction ↓

brain/vision development ↑

AA/DHA blood ↑

3,448 people

Muscle genes up

MPS no change

979 people
Mood balance
Moderate

Improved mood, -17 GDS

AA/EPA shift, mood boost

620 people

AA/Oxylipins ↑; PTB risk

Hormones/stress: cortisol ↓

625 people
Skin repair
Moderate

↓ platelet activation

↑ repair markers

305 people
Skin health
Moderate

Inflammation ↓, +30%

Skin symptoms ↓

AA-mediated irritation ↓

373 people

Lower inflammation, faster recovery

-CK, faster immune rebound

184 people

Anti-inflammatory fatty acids

Joint pain/stiffness ↓

AA:EPA -1.9 pp

175 people

Intake↑; AA↑ (+25%)

Taste↑; AA↑ (+50%)

67 people

DHA↑, AA↓; speed +3%

Walking speed +3%

118 people

PG signaling ↑

IL-6/MuRF-1 ↓

36 people