Lemon Balm

Anxiety/depression ↓

Agitation/crying ↓

Sleep/mood ↑

↓ Anxiety/Stress

↓4‑herb, −1.19 d

↓ Depression/Anxiety

Anxiety/mood ↓

BP/lipids/glucose ↓

Anxiety/stress ↓, calmness ↑

−35% agitation, +30% responders

GIS, 43.3%

Pain/bloating, crying -124m

Anxiety/IBS severity, large

Less pain/bloating

GIS: significant drop

Crying −124 min

Sleep quality: +PSQI, −2.9 ISI

Deep sleep ↑, REM ↓

Memory + cognition

Anxiety/calmness + cortisol

+0.006 vs -0.085

Attention + memory

Calmness + recall

Sleep onset/sleep −2.9 ISI

Sleep disturbance −38%

Sleep onset improved p<0.05

Antioxidant ↑MDA↓

Vitamin E, ‑SH ↑