Black Walnut

BP ↓5 mmHg

Lipids/vascular function

TG↓ LDL↓

Lipids ↓; +5.7%

Mortality ↓28-39%

Weight ↓; BP ↓

Neutral weight: +0.4 kg

Lower intake: -97 kcal

ALA/PUFA ↑

Energy/PUFA targets ↑

SFA ↓, +31% polyphenols

Butyrate microbes, better digestion

Bile acids, cholesterol down

Antioxidant ↑ ORAC/enzymes

Oxidative stress ↓ MDA

Butyrate bacteria ↑

Bile acids ↓

Lipids + HbA1c LDL -6%, HbA1c -0.2%

Glucose/insulin control Insulin response +26%

Mood stability −27.5%

Depression prevented +4.69

Stress biomarker −56.1

Reasoning +11%

Cognition/sleep +8%

Reaction time faster

BP, NO

Bile acids, cholesterol

Faster ulcer healing

-2.6 days

Shorter symptom duration

Anti-inflammatory oxylipins +

Lower IL-6/IL-8

Sleep quality + latency

Melatonin + sleep quality

Sleep quality, duration

Sleep quality, latency

6-SMT up