Proof.Fit

Soy Isoflavones

16 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Heart health
Strong

LDL/TC ↓, BP ↓

Endothelial function ↑

Inflammation/oxidation ↓

4,329 people
Hormone balance
Strong

Hot flashes/symptoms −40–61%

Estrogen metabolism +31% ratio

Androgens/FSH down

4,374 people
Cholesterol
Strong

LDL/TC down

HDL slightly up

3,481 people
Bone health
Strong

Spine/hip BMD ↑

Resorption markers ↓

3,590 people
Fertility
Strong

Androgens/PSA ↓

Estrogen shift 2:16↑

Breast density ↓

11,666 people
Inflammation
Strong

CRP/IL-6 ↓

sICAM-1/VCAM-1 ↓

COX-2/PGE2 ↓

2,161 people
Blood circulation
Strong

BP -18/16 mmHg

LDL -6-9%

FMD +1-5 pp

1,661 people
Antioxidant
Moderate

MDA ↓, TAC ↑

OxLDL ↓, FMD ↑

935 people
Weight management
Moderate

↓ fat mass/weight

↓ insulin resistance

536 people
Women's health
Moderate

Hot flashes/symptoms ↓

Vaginal health ↑

507 people
Skin health
Moderate

Wrinkles ↓, +10%

Hydration/pigment improved

Collagen ↑

293 people
Urinary comfort
Moderate

Urinary leakage -9.5%

Mild symptom relief

308 people
Mood balance
Moderate

Mood symptoms ↓

Depression/anxiety ↓

252 people
Mental clarity
Moderate

Memory/fluency +8.5%

Planning/speed +7%

167 people
Joint comfort
Weak

Muscle/joint pain -10

Hot flashes, dose-related

102 people
Sleep quality
Weak

Sleep quality improved

NHP sleep p<0.001

60 people