Wellbeing

Lipid/weight ↓10-20%

Glycemia/inflammation ↓

cure +99%

parasites fast-clear

anemia ↓

Bone/metabolic: +25(OH)D

Mood/immune: fewer symptoms

Safety: no hypercalcaemia

Hb↑, QoL↑

Transfusions↓, fatigue↓

Pain/sleep gains

+50%

Mood/wellbeing gains

Liver/metabolic: +24% histology

Inflammation/immune: improved markers

GSH+8.4%; endurance

GSH↑; pregnancy↑

GSH↑; HbA1c↓

Pain/opioid ↓

Bowel prep ↑

+20% cleanse

BP ↓10-22 mmHg

Stone recurrence ↓36%

ON/off time +1–2h

Motor scores +2

B12 status +44%

Homocysteine/MMA ↓

Cognition/pain improved

Mental health/QoL ↑

Anemia/immunity/body weight ↓

Vitamin A status↑

Mortality↓ & health↑

Folate ↑; wellbeing +

Wellbeing +10%; mood

Sleep ↑; wellbeing +

Pain/function: better wellbeing

Mood/fatigue: better wellbeing

Anxiety/depression −20.4

Pain/sleep/QoL

Odor/adjustment/QoL

Pain relief +28pp

Muscle/growth benefits

Nutrition/biomarkers shift

Depression relief ~50%

Fewer side effects

Hot flashes/QoL

Psychiatric + CD4

Phe/GI ±114

Motor/QoL gains

DHEA, mood +84%

Vaginal atrophy, pH −0.66

Immune/infection risk ↓

Hb/iron ↑

Improved nutrition, immunity

Psychiatric symptoms ↓

Depression −9.6%

Immune/infection ↓

Growth/recovery ↑

Mood ↓ with TRP loss

Mood/sleep ↑ with TRP

Digestion+milk +11%

Intake+growth ↑

Salmonella ↓

Pain/sleep improves

Anxiety/craving eases

Seizures/spasticity drop

Fatigue/QoL improved

+2 MMSE

Hot flashes/sleep improved

Pain/function ↓ up to 76%

OA risk ↓59%

Lipids ↓; +5.7%

Mortality ↓28-39%

Weight ↓; BP ↓

Cognition +3.3

Daily function improved

Care time -32m

Respiratory/illness recovery

Metabolic/inflammatory benefits

Eye carotenoids +5-fold

Stress/cognition improved

Pain/function improved

Cartilage marker down

UTI reduction: ~50%

Antibiotic use lower

Cold symptoms −16%

Fatigue/QoL ↑

Nausea/pain ↓

Inflammation/pain ↓

Cognition/wellbeing ↑

QoL improved

Stress/cortisol ↓

Sleep/recovery ↑

Mood/cognition ↑

Pain/stiffness -12.2

Allergy symptoms reduced

CD4 +105 cells/µl

GI comfort + well‑being

1–2 month gains

Infection/cold reduction

Anxiety/wellbeing −8.4

Pain/symptoms −57%

Pain/function ↓

Mood/anxiety ↓

Olfaction/QoL ↑

Urinary relief +4-7 pts

Skin healing/pain −3 pts

LDL down ~10-27%

Better survival/QOL

Less fatigue/infection

Anxiety/mood ↓

BP/lipids/glucose ↓

Lipids/BP: -25%

+HDL, fewer events

Platelets: -48.7% HPR

Symptom relief, +60pp

Metabolic/liver, improved

Mood/depression ↓

Inflammation/health ↓

Symptom relief ~-70%

Fewer side effects

No endometrium increase

Metabolic/inflammatory improvement

Venous symptoms/QoL

Pain/function improved

Immune response boosted

Pain/function ↓64%

Bleeding/QoL ↑

Lower fat & LDL

−17% intake

Improved attention, sleep

Anxiety -9.9

Remission +20%

Hormones/symptoms +39%

Lipids/inflammation/BP improved

Cold symptoms −3.85

Throat/nasal symptoms improved

Inflammation & function

Ulcers/anemia improved

Dry eye/skin better

Cognition +10%

IBS/UC symptoms ↓

Soy allergy tolerance

Urinary symptoms/flow

Safety: minimal changes

Mood/anxiety: improved

Sleep/stress/pain: improved

Cold relief, fewer infections

Wellbeing up, anxiety unchanged

Menopause symptoms ↓73%

Mood/anxiety ↓77%

Menstrual pain −2.48

Blood pressure down

LDL/inflammation −26–47%

Heart events/death −44–64%

Fatigue/activities unchanged

Cognition/lipids: better

Sleep/GI: improved

Fatigue/immune +QOL

Fitness/BP +4.1 VO2

GI symptoms/fatigue, -20%

Allergy symptoms/medication, IgE -36%

Growth/feed +7-10%

Antimicrobial activity

Bleeding ↓ PPH 11.1%

Bleeding ↓ after abortion

UTI symptoms ~no change

Antibiotics −8% / −64%

Rhinitis symptom relief

Better with higher dose

Urination +35%

Symptom/QOL improved

Flow +1.6-2.0

Weight/fat loss −7.4kg

Glucose/appetite +GLP-1, −25.3%

Gingival inflammation biomarkers ↓

Urinary symptoms/flow improved

Better oxygen, less inflammation

+1.8%, -15.7 mg/L

Weight/waist ↓, HDL↑

Glucose/lipids improved

HbA1c/weight ↓

microbiota/neuropathy ↑

Glucose control, -1.15% HbA1c

Insulin resistance, lower FPG

Menopause symptoms ↓

Milk volume ↑

Urticaria, sleep, QoL

Waist -4 cm

Biotin turnover ↑69%

Hoof growth +15%

Wound healing, -40%

UTI episodes, -0.35/mo

Weight/fat loss, +2.7kg

Less swelling, cramps

Faster healing, better scars (-6.9 days)

Antioxidant boost (+8-10%)

Wellbeing improved

Pain/swelling/tiredness +11-24%

Sleep, mood, anxiety improved

Irritability/libido/asthenia improved

Mortality/rehospitalization ↓13.3%

Shorter stay, better recovery

Lower glucose/inflammation

↓FPG, ↓HOMA-IR, ↓hs-CRP

Cognition +0.14

Ketones +13.19

Wounds/activity ↓ 5.9%

Safe, mild AEs

Fewer severe side effects

QOL + at 5w

Better baseline recovery 6m

Inflammation down, wellness up

IL-6/CRP/lymphocytes ↓

Inflammation reduced, wellness up

IL-6/CRP/lymphocytes down

Burnout/mood improved

Depression lower

BMI, visceral fat ↓

subcutaneous fat unchanged

Hot flashes ↓ ~70%

Menopause symptoms ↓

Blood sugar control

Vessel function

Higher omega-3 status (+0.49%)

Better fatty-acid balance (-4.1)

T3↑ T4↓

QoL same; symptomatic subgroup improves

↑ energy use +18.6%

↓ belly fat, weight

Liver markers -44%

Carotenoid uptake 4.8x

Cs burden -63%

Lower radiation exposure

Less pain, +PPT

Lower stiffness

Pain −5.23

QoL, flow

Less mucositis, +40pp

Saliva preserved, -31%

Climacteric relief −66%

Hormones unchanged

Vaginal health, symptoms +FSFI

VHI, pH, symptoms improved

Cholesterol down; weight unchanged

LDL −28.7 mg/dL

Antioxidants up; stress down

Liver enzymes down

Faster processing speed −6.7%

Lower stress −9.51

Depression improved; BAG younger

No group differences

Weight loss, cholesterol ↓

GLP-1 ↑, −5.0 kg

Butyrate, insulin, triglycerides

+17.4%, TG down

Sugar intake -42%

Cravings, chocolate desire

Motor/ON time +25–70%

QoL/symptoms similar; AEs +18.5%