proof.fit

Milk Thistle

14 benefits mapped to clinical evidence across supplements.

Benefit Evidence

ALT/AST ↓

Fibrosis/stiffness ↓

689 people
Metabolism
Moderate

Glucose/insulin ↓, HOMA-IR ↓

Lipids ↓, HDL ↑

845 people
Cholesterol
Moderate

LDL down ~32%

Total cholesterol down

591 people
Inflammation
Moderate

Lower hs-CRP

↓6.8%

↓26.8%

421 people
Cell health
Moderate

Liver fibrosis/stiffness ↓

Oxidative/inflammatory markers ↓

272 people
Blood sugar
Moderate

Lower FPG/HbA1c (~20%, ~12%)

Lower FBS, insulin dose

Improved insulin resistance

326 people
Skin health
Moderate

Less dermatitis/mucositis

Better wound healing

201 people
Antioxidant
Moderate

Antioxidant ↑ SOD/GPX

+12.85%

+30.32% GPX

180 people

Mucositis/HFS ↓ delayed

Wound/AKI recovery ↑

187 people

Liver enzymes normalise

Ferritin/AKI reduced

157 people

Hot flashes -69%

Menopausal symptoms down

80 people

Hot flashes ↓ ~70%

Menopause symptoms ↓

80 people

GIS symptoms - p<0.05

Earlier relief vs placebo

60 people

↓TNF-α, neopterin

↑IFNγ/IL-4

30 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Milk Thistle

Search all

878 products whose verified label declares Milk Thistle — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.