Glucosamine

8 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Strong

Pain/function relief −76%

Joint-space loss −0.25 mm

9,822 people

Strong

Pain/function ↓; JSW preserved

Inflammation/biomarkers ↓; mobility ↑

9,654 people

Strong

Pain/function ↓ ~25-50%

Less NSAID use

Joint space preserved +0.3mm

6,602 people

Strong

Pain/function improved

JSN slowed ~0.3mm

Surgery risk down 57%

4,719 people

Strong

Pain/function ↓ up to 76%

OA risk ↓59%

3,314 people

Joints & tendons

Strong

Joints: ↓JSN ~0.25mm

Tendons: no clear data

3,037 people

Muscle soreness

Strong

Pain/function −50%

Soreness relief longer

Responder rate +24%

1,886 people

Illness recovery

Moderate

Pain/function improved

Faster recovery +73%

718 people

Main Effects

Pain/function relief −76%

Joint-space loss −0.25 mm

Strong

9,822

Pain/function ↓; JSW preserved

Inflammation/biomarkers ↓; mobility ↑

Strong

9,654

Pain/function ↓ ~25-50%

Less NSAID use

Joint space preserved +0.3mm

Strong

6,602

Pain/function improved

JSN slowed ~0.3mm

Surgery risk down 57%

Strong

4,719

Pain/function ↓ up to 76%

OA risk ↓59%

Strong

3,314

Joints & tendons

Joints: ↓JSN ~0.25mm

Tendons: no clear data

Strong

3,037

Muscle soreness

Pain/function −50%

Soreness relief longer

Responder rate +24%

Strong

1,886

Illness recovery

Pain/function improved

Faster recovery +73%

Moderate

718