Type-II Collagen

9 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Joints & tendons

Strong

Collagen breakdown ↓

Pain/function ↑

JSN/erosion ↓

16,686 people

Strong

Pain/function better

Cartilage markers↓

13,578 people

Strong

Pain ↓, function ↑

CTX-II ↓ or ↑

3,368 people

Strong

Pain/function ↑

CTX-II/PRO-C2 ↓

JSN progression ↓

8,821 people

Strong

Pain/function improvement

Biomarker shifts -31%

2,426 people

Strong

Pain/function improved

Cartilage marker down

1,386 people

Workout performance

Moderate

Pain/function + movement

Strength/body mass gains

653 people

Illness recovery

Moderate

Pain/function ↑; relapse

Wound healing ↑ (~2x)

Cartilage marker ↓, pain ↓

524 people

Muscle soreness

Moderate

Pain ↓; function ↑

CTX-II ↓; soreness ↓

416 people

Main Effects

Joints & tendons

Collagen breakdown ↓

Pain/function ↑

JSN/erosion ↓

Strong

16,686

Pain/function better

Cartilage markers↓

Strong

13,578

Pain ↓, function ↑

CTX-II ↓ or ↑

Strong

3,368

Pain/function ↑

CTX-II/PRO-C2 ↓

JSN progression ↓

Strong

8,821

Pain/function improvement

Biomarker shifts -31%

Strong

2,426

Pain/function improved

Cartilage marker down

Strong

1,386

Workout performance

Pain/function + movement

Strength/body mass gains

Moderate

653

Illness recovery

Pain/function ↑; relapse

Wound healing ↑ (~2x)

Cartilage marker ↓, pain ↓

Moderate

524

Muscle soreness

Pain ↓; function ↑

CTX-II ↓; soreness ↓

Moderate

416