Skin health
95 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
Psoriasis control; +70% PASI
Vitiligo repigmentation; +35%
Wound healing; -88%
Infection↓; PI -13%
Healing↑; 3 days
Barrier/healing +7pp
Acne/dermatitis reduced
-35 days wound
Thicker, less pigmented skin
Less irritation, better tolerance
Pigment/texture +MASI
Barrier/hydration -TEWL
Pigment/brightening +1.3
Wound/scar healing improved
Anti-wrinkle/hydration +28%
Photoprotection, antioxidant
Wound healing, scars
Acne inflammation ↓
Wound healing ↑
Hydration↑, TEWL↓
Eczema/psoriasis↓, itch↓
PUFA↑, inflammation↓
Eye/retina: MPOD +15%
Skin carotenoids: +42%
Wound healing +50%
Skin inflammation +function
Cancer risk +17%
Healing + infection↓
Pain/swelling↓, healing↑
Skin redness↓, hydration↑
Demodex/OSDI −5.5
Hand microbes −10%
Athlete’s foot +72%
Hydration/barrier +TEWL
Redness/inflammation ↓
Healing/repair faster
Antioxidant photoprotection + skin redness
Carotenoids/pigmentation +10-67%
Skin hydration/elasticity
+26%, +5.7
Pigmentation/redness/wrinkles:-19.5%
Wound healing +60%
Pruritus/psoriasis improved
Hydration up, TEWL down
Wrinkles/photoaging; +31% elasticity
Infection prevention; -29% ATIs
Skin healing improved
Inflammation/oxidation reduced
Healing + elasticity
Acne + barrier
Wrinkles -7%
Collagen +30g
Healing +34%
Less itch, pain
Faster healing, more clearance
Skin aging/redness ↓
Eczema/psoriasis barrier ↑
Ulcers/swelling/bruising ↓
Hair growth ↑
AK lesions −24%
Skin polyamines ↓
Lightening/depigmenting skin
+10–13%,−18–21%
Repigmenting vitiligo skin
Better skin severity
Less itching/pain
Less pain, more satisfaction
+12 min sleep
Faster skin prep
Collagen +37-41%
Pigment/lightening improvement
Wrinkle reduction
Inflammation/lesions ↓; −22% RID
Pigmentation/scar repair ↑
Redness/angiogenesis ↓; −14.6% HIF-1α
Fungal cure +2%
Microcirculation +22%
Inflammation ↓, +30%
Skin symptoms ↓
AA-mediated irritation ↓
Elasticity/texture +9%
Pigment/spot reduction
Scar healing +91.4%
Flap ischemia/necrosis ↓
Mouth opening +5.5 mm
Barrier/pigment ↓
Inflammation/pain ↓
Skin carotenoids +31-46%
UV redness -25-48%
Collagen/AR ↑
Oil/brightness +
Wrinkles ↓, +10%
Hydration/pigment improved
Collagen ↑
Repigmentation/healing +90%
Photoageing/roughness -50.8%
Less dermatitis/mucositis
Better wound healing
Wrinkles/elasticity/hydration improved
UV resistance +5 mJ/cm2
Immune/recurrence: improved
Hydration/repair: +68.2%
Barrier +25%/−20%
Flushing −50%
Itch −28%
Bruising severity -20%
Rash severity women
Lightening, similar to HQ
Hydration/elasticity: +10-26%
Insulin/androgens ↓ 62%/55%
Skin barrier ↑ hydration 50%
PPE/HFS ↓ incidence
QoL/pain improved
Vascularity/pigment ↓
MASI −1.2
Wrinkles −17%
Hydration↑, TEWL↓
Pigment/erythema↓
Pigment area↓ (~45%)
Barrier + hydration
DGLA / symptoms
Hydration, TEWL
Wound closure, TNF
Redness, melanin, hydration
Irritation/redness ↓
Wrinkles/elasticity ↑
Healing & pain: ~6.7d
Redness/inflammation: reduced
Angular stomatitis 30.4%→0%
Acne lesions ↓; less irritation
Dry mouth, QoL
VVC symptoms, better
Pigmentation −12%
Wrinkles/smoothness +14%
Pain/inflammation ↓
Ulcers healed faster
Healing score, pain ↓
Acne severity ↓
Itch relief 82%
Hyperpigmentation ↓0.56
Acne lesions ↓
Acne severity ↓
Vitiligo repigmentation + irritation
Hair regrowth, SALT ↓
Pain relief, healing faster
Burning/lesions ↓ ~90%
Faster healing, -0.8 days
Less pain, itching
Healing faster: -30d
Less breakdown markers
Better nitrogen balance
↑ Carotenoids; ↓ UV erythema
↓ UV genes; ↑ protection
Barrier, texture improved
Radiodermatitis delayed
Texture: no change
Pigment: ↓ melanin
Carotenoids: +27%
Brightening: MI −10.2%
Hydration/elasticity: R2 +28%
Redness ↓; tinea signs ↓
UV erythema, fungal infection
Collagen synthesis +94-165%
Microperfusion, collagen genes
Itch −55%; eczema
Wrinkles/pigment/redness −20–30%
Laser downtime/erythema ↓
Mucositis 1.5d vs 19d
Retinol, D3 ↓
Backfat, marbling ↑
Dermatitis unchanged
Itch/pain ↓11%
Ulcers, +2.03%
Hand-foot syndrome, +26%
Swelling ↓, +73% mouth opening
Pain unchanged
Cure↑ 94.74%
Relapse↓ 16.00%
Barrier, hydration, elasticity
TEWL -1.23; hydration +3.66
Hair density +14/cm²
Hair elasticity/diameter +58 gf
Roughness/fine lines/elasticity
-
Erythema/steroid use
Wrinkle reduction; collagen↑
Eye wrinkles, roughness↓
Wrinkles −10.6%; smoother skin
Elasticity +12.4%; antioxidant +20.8%
Repigmentation + significant
Burning, redness + piperine
Hair count +29
Shedding reduced
Hydration ↑, TEWL ↓
Dryness/itch ↓, meds ↓
Moisture, elasticity ↑
Itching ↓
Less staph, lower severity
~95% fewer staph
Aesthetic, elasticity, thickness
Elasticity +9.36%, thickness +8.42%
Stomatitis severity down; similar to miconazole
Candida counts down
Hydration, barrier, blood flow
+ hydration, - TEWL
Redness,papules,h hydration
Itching improved
Moisture/elasticity ↑
Itch ↓
Leishmaniasis lesions: ~80% improved
Parasite activity: in vitro
KOH negativity, itch
non-inferior vs terbinafine
Skin/subcutaneous fat +5.5%
Limb size +2.3%
Acne improvement +2.6%
Less pain, fewer side effects
Hydration ↑17.35, TEWL ↓4.41
Redness ↓54.61