proof.fit

Manganese

14 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Antioxidant
Moderate

MnSOD ↑, MDA ↓

Oxidative stress ↓

1,884 people

Joint pain −27%

Exam score −43%

1,615 people
Cell health
Moderate

Kidney protection

+BUN/Cr, −AKI

Reduced neuropathy symptoms

1,175 people
Nerve health
Moderate

CIPN reduced: 1.6 vs 2.3

Motor function worsened

831 people
Fertility
Moderate

+1.1% laying rate

better litter/hatchability

sperm integrity: dose-sensitive

738 people
Brain health
Moderate

Neuropathy ↓; OR 0.62

Motor signs/tremor ↑

AIMS response +46.2%

579 people
Bone health
Moderate

Spine BMD: +1.48%

Bone Mn: dose-dependent

1,107 people

Pain -27%

Exam/severity -43%

207 people

Absorption/retention +

Lesions/cholestasis +

3,599 people

Milk +3.3 kg/day

Immune markers ↑

Antibody/PBMC/IFN-γ ↑

67 people

Mn absorption ↑2.3x

Fat/oxidation ↓, MnSOD ↑

336 people

Laser downtime/erythema ↓

Mucositis 1.5d vs 19d

223 people

Downtime/erythema reduced

SOM 1.5d, −22%

223 people

Trace intake; no serum change

Growth +14.38%

62 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Manganese

Search all

433 products whose verified label declares Manganese — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.