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Berberine

16 benefits mapped to clinical evidence across supplements.

Serves the goals:CardiovascularDetoxEnergyEssential HealthGut Health

Benefit Evidence

Metabolism
Strong

Lipids/Glucose ↓

Liver fat/ALT ↓

Insulin resistance ↓

3,504 people
Cholesterol
Strong

LDL/TC −

TG/HDL +

2,799 people
Blood sugar
Strong

Lower glucose/HbA1c

Lower insulin resistance

2,524 people
Heart health
Strong

LDL/TC ↓

Inflammation/arterial function ↓

2,622 people
Inflammation
Strong

Inflammation ↓; CRP/IL-6

Inflammation ↓; 35%→20%

Fibroinflammation ↓; ALT −4.8%

1,336 people
Gut health
Strong

H. pylori: +50%

Diarrhea: -30%

2,577 people
Cell health
Strong

Liver fat/enzymes −5%

Glucose/lipids −1%

2,536 people
Weight management
Moderate

Weight loss, fat -3.5kg

Glycemia/lipids, less weight

Fat loss, waist/BMI

1,238 people
Digestive support
Moderate

H. pylori/ulcer: +clearance

Diarrhoea/IBS: -30% stools

Adenoma recurrence: -11%

3,404 people
Liver support
Moderate

Liver fat, ALT −5

Lipids/insulin, liver support

ALP/cholestasis, liver enzymes

955 people
Hormone balance
Moderate

Androgen↓, SHBG↑

Insulin resistance↓

1,082 people
Healthy aging
Moderate

Lipids/IR −31%

Adenoma recurrence −11%

Heart function, fewer deaths

1,894 people
Immune support
Moderate

Reduced inflammation

Immune marker gains

663 people
Skin health
Weak

Pain/inflammation ↓

Ulcers healed faster

Healing score, pain ↓

150 people
Energy & Fatigue
Weak

↑ LVEF, walk capacity

↓ VPCs; 7 vs 13 deaths

156 people
Blood pressure
Weak

BP −8 mmHg

Aortic BP −10.4

70 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Alpha-Linolenic Acid

Shares 12 benefits: blood pressure, cell health, cholesterol, energy & fatigue

Chlorogenic Acid

Shares 12 benefits: blood pressure, blood sugar, cell health, cholesterol

Phytosterols

Shares 12 benefits: cell health, cholesterol, digestive support, healthy aging

Epigallocatechin Gallate

Shares 12 benefits: blood sugar, cell health, cholesterol, energy & fatigue

Akkermansia muciniphila

Shares 11 benefits: blood sugar, cholesterol, digestive support, energy & fatigue

Resveratrol

Shares 11 benefits: blood sugar, cell health, cholesterol, energy & fatigue

Products with Berberine

Search all

97 products whose verified label declares Berberine — not every bottle that mentions it in a title.

THORNE

THORNE Berberine, Dual Action Phytosome & HCl Formula, 60 Capsules

Berberine Hydrochloride 450 mg · Berbevis 550 mg

$44.00Herbal Supplements

Integrative Therapeutics

Integrative Therapeutics® Berberine

Berberine Hydrochloride 500 mg

$32.75Herbal Supplements

Natural Factors

Natural Factors WellBetX Berberine 1,000 mg per Serving, 120 Veg Caps

Berberine 500 mg

$34.97Herbal Supplements

Nutrivein

Nutrivein Berberine Supplement 1200 mg with Ceylon Cinnamon

Berberine (Berberis Aristata 10:1 Extract) (Bark) (Equivalent to 12,000mg Berberis Aristata Powder) 1200 mg · Organic Ceylon Cinnamon Extract 10:1 (Cinnamomum verum) (Bark) (Equivalent to 200mg of Ceylon Cinnamon Powder) 20 mg

$26.99Cinnamon

NutriFlair

NutriFlair Organic Ceylon Cinnamon (100% Certified Organic Ceylon

Chromium 500 mcg · Ceylon Cinnamon 1000 mg · Berberine 200 mg +1 more

$25.19Cinnamon

Ancient Bliss

Ancient Bliss Berberine HCL 1200mg with Ceylon Cinnamon, Bitter

Berberine 1200 mg · Organic Ceylon Cinnamon 100 mg · Organic Bitter Melon 100 mg +1 more

$24.99Cinnamon

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.

Nutritional Supplementation on Physiological and Metabolic Markers in FemalesBerberine · Perimenopausal Women, Body Composition Changes · 80 participants planned · ClinicalTrials.govRecruitingEvaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal DiscomfortBerberine · Intestinal Discomfort, Abdominal Pain/ Discomfort · 140 participants planned · ClinicalTrials.govRecruitingA Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 DiabetesBerberine · Prediabetes / Type 2 Diabetes · 90 participants planned · ClinicalTrials.govRecruiting