Proof.Fit

Pine Bark Extract

18 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Main Effects
Vascular health

Endothelial function +41%

Venous swelling/thrombosis ↓

Strong
1,070
Blood circulation

Vasodilation +41% FBF

Blood pressure -7.5 mmHg

Edema/leakage reduced

Moderate
897
Healthy aging

Skin aging: +9%, -6%

Menopause symptoms: -56%

Blood sugar/BP: ↓

Moderate
986
Swelling relief

↓ edema/swelling

↓ edema, pO2

Moderate
787
Antioxidant

Oxidative stress ↓

Antioxidant status ↑

Moderate
769
Inflammation

Lower inflammation markers

IL-6/CRP/LEU ↓

Reduced tissue inflammation

Moderate
649
Heart health

Endothelial health, +41%

Blood pressure, -7.5

Moderate
396
Joint comfort

Pain reduced

Joint function improved

Moderate
374
Skin health

Elasticity/texture +9%

Pigment/spot reduction

Moderate
334
Skin repair

Wound healing up

Bleeding/symptoms down

Moderate
216
Eye health

Retinal swelling/leakage -15μm

+10 cm/s flow

Allergy eye symptoms -35%

Moderate
212
Blood sugar

Glucose control −24 mg/dL

HbA1c −0.8%

Postprandial glucose −14%

Moderate
211
Oral health

↓ bad breath, tongue plaque

↓ bleeding, plaque build-up

Moderate
203
Allergy relief

Eye/nasal symptoms −35%

IgE rise −12.5%

Weak
118
Blood pressure

SBP ↓3–7 mmHg

BP meds ↓50%

Weak
110
Energy & Fatigue

Energy/fatigue +17%

Energy/fatigue -42.8%

Energy/fatigue improved

Weak
170
Endurance

Endurance +17%

NAD+ boost

Pain/walking improvement

Weak
156
Focus & concentration

Attention↑, hyperactivity↓

Oxidative stress↓, GSH/GSSG↑

Weak
61