MSM

4 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Moderate

Pain/function −2.8

NSAID use ↓

Pain/function +6.8s

615 people

Moderate

Pain ↓, function ↑

Knee mobility ↑, pain ↓

455 people

Weak

CSMS −20.3%

IgG4 6×

2,426 people

Weak

Redness,papules,h hydration

Itching improved

46 people

Main Effects

Pain/function −2.8

NSAID use ↓

Pain/function +6.8s

Moderate

615

Pain ↓, function ↑

Knee mobility ↑, pain ↓

Moderate

455

CSMS −20.3%

IgG4 6×

Weak

2,426

Redness,papules,h hydration

Itching improved

Weak

46