Proof.Fit

Alpha-Ketoglutarate

10 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Main Effects
Muscle growth

Protein anabolism +20%

Less catabolism; faster healing

Better strength/power

Moderate
829
Exercise recovery

Protein balance +20%

Wound healing -30d

Moderate
228
Skin repair

Fast graft closure +31d

Less protein breakdown

Moderate
321
Stress resilience

Nutrition↑, +127g

Wound healing↑, -16d

Moderate
308
Skin health

Healing faster: -30d

Less breakdown markers

Better nitrogen balance

Weak
101
Detoxification

GSH/vitamins +40%

Neopterin -30%

Acrylamide excretion ↑

Weak
95
Endurance

Aerobic performance +VO2max

Power maintenance +7.3%

Weak
77
Healthy aging

More appetite, weight, independence

QoL improved, lower costs

Weak
194
Bone health

Bone resorption −37%

Bone thickness +21%

Weak
76
Energy & Fatigue

Lower injury, lactate

More α-KG, power

Weak
58