Niacin

LDL↓ HDL↑

TG↓ +39%

HDL↑ LDL↓ events↓

IMT↓ 0.01mm

HDL↑ TG↓ LDL↓

Glucose↑ insulin resistance↓

HDL↑ LDL↓

CIMT/FMD +22%

Blood flow↑

Atherosclerosis slowed

HDL/LDL improved

Barrier +25%/−20%

Flushing −50%

Itch −28%

Fuel shift: FFA↓, carbs↑

NAD+ boost: ~2x

↓ flushing, GI AEs

no serious-AE rise

Recurrent MI ↓

15-year mortality ↓14%

Phosphorus -0.7 to -1.0

Albumin improved

HDL up, CRP -15%

Triglycerides -15%, Lp-PLA2 -20%

Leptin +2.38; FFA ↓

Leptin +26.8%; HOMA +42%

Improved dementia ratings

Boosted blood flow