Mental clarity
99 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
Iron repletion: clarity +
Cognition link: Hb/ferritin
Attention/working memory +0.8
Executive function/remission +70%
Reaction/memory +
Alertness/EEG +
Executive/processing +24s
Memory/attention +18%
Ammonia↓, cognition↑
Memory/attention↑
Cognition↑, −1.75
Memory+executive
B12↑,Hcy↓
Brain atrophy↓40%
Memory + cognition
Attention + EEG
-3.2 ADAS-cog
Folate/B12 better clarity
Omega-3 boosts folate
Mental clarity +0.9
Thinking/motor +4 tests
Cognition +2.1 points
Better cognition +2
Mixed behavior/attention -37%
Improved neurodevelopment +14.8pp
Cognition +3.6 pts
Function/global better
Attention/behavior improved
Phe↓/LNAA↑, clarity↑
Phe↑, clarity↓
Memory +0.07 SD
Attention speed +8.5%
Anxiety/stress reduced
Attention/memory +1.25d
Fatigue/stress ↓
Global cognition +2pt
Memory/cognition +hcy
Brain atrophy −30%
Cognitive recovery +14%
Stroke lesions -25%
Postop confusion -50%
Tyrosine boosts attention
and working memory
+38 ms reaction time
Memory/attention +
Mental fatigue -
+29% cognition
Attention/working memory +
Fatigue/stress clarity +
Memory↑, clarity↑
Attention↑, faster 3-5%
Inflammation↓, clarity↑
Migraine fewer, clearer
Memory/attention + mood
Ammonia↓, clarity↑
-15.4% recurrence
Memory worse
Attention/reaction better
-77% TRP
Cognitive scores, slight gains
Oxidative stress, improves
Memory/attention +
Hepatic confusion/ammonia -
Stroke/function +
Memory/attention: +13%
AD decline: slower
Cognitive recovery +29%
Auditory plasticity/MMN +7-14%
Memory/attention/orientation +
ADAS cognition/global +
Better cognition +0.73 z
Perfusion/performance +7% to +85%
Negative symptoms ↓ ~36%
Cognition/attention slightly improved
Word learning + retention
WM/attention +3 mo
PD cognition peak-dose
Cognition +0.8
Dementia severity
Stroke recovery
Global cognition +9
Attention/memory +
Reaction time +
Better cognition
Memory/clarity +3.2
Brain development
Cocoa: better alertness
Pentoxifylline: modest cognition
Clarity/work memory +4.9
Calmer, less drowsy
Faster math/processing
Attention/memory +5
EEG/fMRI activation
+10% NAA
Attention +5-8%
Reaction time -17 ms
Mental fatigue reduced
Memory/attention +sage
Fatigue/alertness +peppermint
Cognitive tests +
Memory/MMSE 79%
Behavioral scores +
Cognition +11 points
Memory/behavior 58%
Cognition/ADL +4.6
Memory + cognition
EEG + attention
Attention/accuracy ↑
Fatigue/burnout ↓
Clearer processing (+p<0.05)
Behavior improved (−34%)
ADHD symptoms improved (d>1.0)
Alertness↑ anxiety↓
Memory↑ anxiety↓
Cognition↑ speed↑
Memory/attention + stress
Stress/fatigue - p
Mood/memory +
Sharper cognition/negative symptoms
~19-30% better
Global psychiatric gains
faster, sharper attention
−30 to −150 ms
Cognition + function
Neurology recovery
Better blood flow
Cognition +0.3 MMSE
Fatigue, learning
Development +0.7 motor
Memory + cognition
Anxiety/calmness + cortisol
+0.006 vs -0.085
Memory/cognition +0.7
Neurochemistry/metabolism +0.4
Cognition/fatigue ↑
Anxiety/pain ↓
Delirium −11.2%
Memory +3.5; clarity
Attention/speed +, impulsivity -
Better cognition/mood
Less cognitive decline
Attention +42%
Mood/clarity, sleep, HE
Memory/fluency +8.5%
Planning/speed +7%
Ketones↑, cognition↑
Inhibitory control↑, WM↑
Mood/depression -44%
Sleep/mood/focus improved
Memory/attention +
+14.4% BDNF
Prefrontal blood flow +
Faster attention RTs
Better ERP attention
+38 ms
Cortisol ↓, attention/memory ↑
Working memory ↑, cortisol ↓
SAM ↑, cognition ↑
DAT/metabolites shift
Less fatigue, better focus
Brain oxygenation, no clear clarity
Inflammation/BDNF:+21%
Cognition/attention:+
Attention/speed +
Memory/function +6.23
Emotion/sleep +
Clearance faster; cognition unchanged
Negatives improved; cognition unchanged
Processing speed + cognition
Fatigue recovery - oxidative stress
Cognition +8/15
Function +0.02
Stability 7/15
Memory +0.17
Cognitive score +6.25
BDNF +12.1%
Wearing-off: UPDRS -4.2
ADHD symptoms: ~34% vs 18%
Better cognition, less sleepiness
ADAS-Cog ~29% better
MDRS + verbal fluency
Reasoning +11%
Cognition/sleep +8%
Reaction time faster
Faster processing, +6.7%
Less stress, more recall
Faster reaction, happier
Memory + anxiety: p<0.05
Attention/speed/accuracy: p<0.05
Memory/language ↑
Attention/speed ↑
Alertness/attention ↑
Sedation/analgesia ↓ -60min
Better clarity; NIHSS improved
Inflammation lower; MMP-2/MMP-9, CRP
Alertness/reaction: improved
Cognition/EEG: improved
Cognition + MMSE
Lipids unchanged
IQ +4.1
DHA boost
Faster reaction time
CBF trend, no change
T3↑ T4↓; clarity
Symptomatic subgroup +0.0008
Fatigue ↓; clarity ↑
BAP ↑; RT variability ↓
Clinical/EEG gains
Working memory + mood
Fatigue ↓17.8; cognition ↑14.4
QOL ↑14.1; fatigue ↓16.5
Antioxidant boost, +BDNF/IGF-1
Memory gains, reduced oxidation
Cognition +29%
Brain structure/metabolites
BP −17/−12
Cerebral flow ↑
Memory + recall
Working memory - errors
CERAD + visuospatial
Cognition +2.5%
Cell hydration
EEG slowing, attention -
Memory, slower responses
Memory +8.9%
Attention; insulin ↓4.63
Attention/speed/accuracy +
Fewer errors trend
Early attention ↑
Emotional salience ↓
Mood - anxiety ↓
Attention/memory +
Mental acuity improved
Fatigue/stress reduced
Better mental clarity
Ketones +16% brain energy
Mild memory gains
QoL, motor: similar
AEs +18.5%