NADH

Fatigue↓; NAD+↑

Energy recovery +3.5d

Fatigue/recovery +31%

Physical function +15%

Cognition/sleep improved

Fatigue, +responder

Recovery, +3-4 days

Endurance +15%

Aerobic capacity +10.3%

Fatigue/walk +20%

Aerobic threshold +10%

NAD boost; glycemia/insulin

Metabolic markers; weight/BP

Sleep quality, +PSQI

Sleep duration, improved

Sleepiness, reduced

Cognition, sleepiness +29%

Memory/fluency preservation

Attention lapses reduced

Cognitive +29%

Sleepiness reduced

Attention lapses down

Better cognition, less sleepiness

ADAS-Cog ~29% better

MDRS + verbal fluency

Recovery +15%

Activity +0.45

Stress resilience: cortisol -

Stress resilience: anxiety/HR -8.1

Stress resilience: glucose/redox +10%

Skin barrier +70%

Blood NAD + walk +157m

NAD↑, walk +157m

QoL↑, motivation confidence

Cognition +29%

Hippocampus preserved

Better cognition, less sleepiness

4 measures improved