Endurance
79 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
Iron stores +Hgb
Endurance +VO2
Hb maintained
+1.3 g/dL
Transfusion reduced -83%
Cognition/alertness +
ADHD symptoms +
Mood/euphoria +
↑ exercise tolerance
↓ angina/ischemia
Strength/power +10-30%
Less fatigue; water +1 kg
Pain/function ↓ ~75%
NSAID use ↓
Endurance +2.2 min
Buffering +6.4s/3.2s
Hydration +22 min
Endurance +3-51%
Power/RPE: improved
Endurance: +25.8% time
Endurance: +36% motor
Endurance: +1.97 ALSFRS-R
Endurance time +45%
Walking distance +73%
Ammonia↓, cognition↑
Recovery↑, stay↓
BCAA/Leu: better endurance
Lower fatigue, +performance
Endurance + walking
Fatigue + strength
GSH↑, TTE↑ +8.4%
Oxidative stress↓, performance↑
Endurance +24% TTE
Strength/lean mass gains
Glycogen sparing −19
Glucose↑,fat↓
ATP recovery↑
Blood flow/endurance +14%
Fatigue/muscle loss -14%
MPOD +10–35%
Contrast/vision faster, clearer
Walking +30-400%
LVEF +12%
Soreness/reaction improved
Endurance: ↑20%
Exercise tolerance: +30%
Walking endurance ↑
Altitude tolerance ↑
VO2max +6%
VO2/performance +5%
Blood pressure -9 mmHg
Fatigue/function improved
Performance/endurance +11%
Aerobic capacity +13%
Walk/endurance +6MWD
Muscle/lung endurance
Endurance: +22% work
Endurance: +16% work
Endurance: +1.4 g/dL Hb
Endurance +15%
Aerobic capacity +10.3%
Endurance capacity +14%
Exercise economy/strain reduced
Walking distance +32 m
Exercise capacity +10%
Symptoms/QoL improve
Cardiac workload lower
TTE/thresholds +13%
Power/endurance reps +22%
Exercise + recovery
Walking +33–69%
DHEA-S ↑, endurance +
Exercise + DHEA-S
+10% DHEA-S, endurance
Power/time fatigue +11%
+36% fatigue
Endurance/NO kinetics
VO2max, endurance +3–4%
RPE, fatigue ↓
Jump/power +7–15%
Strength/size + recovery
Endurance: VO2max/time
Endurance +20%
Oxygen use ↓
Recovery faster
Endurance +18.1 m
Muscle preservation +1,019 g
Endurance: +VO2max
Threshold/delay: +9.1% OBLA
Recovery: 24h work capacity
Faster, +power
Better fat use
Cognition, reaction time
+8.97 LOTCA
Attention, cognition
Weight/fat ↓
Stamina/alertness ↑
Cognitive vigilance +7.1pp
Memory/perception
Aerobic/threshold +20%; lactate −27%
Power +3.2% / +38W
Endurance↑ 6MWD/finish
Endurance↑ recovery
Endurance +muscle
VO2max +5-10%
Walk +33-61 m
Endurance: +21.6% VO2max
Endurance: +6MWD, stair-climb
Endurance: ammonia lower
Repeated sprint +4–21%
Short endurance +1–18%
Memory/cognition +58%
Daily function +4.6
Exercise tolerance +53s
Heart function/QoL +25.8
Better memory/attention
Less stress/fatigue
Aerobic endurance, VO2max
Work capacity, well-being
Recovery + blood counts
Arrhythmia markers -7.7 ms
Peak HR +11.9 bpm
Respiratory decline ↓ +6.27%
Inspiratory reserve ↑ +5.78%
Strength +7.7%
Lactate ↓
Knee strength +10.2Nm
Aerobic performance +VO2max
Power maintenance +7.3%
Lower O2 cost +25%
Longer time-to-exhaustion +22%
Pain/function +1.1,+3.1
Better VAS/global ratings
Endurance +11.6%
Lactate/HR improved
Recovery +4.8%
Strength preserved +1kg
Endurance +17%
NAD+ boost
Pain/walking improvement
Cognition, EEG improved
Sprint performance +23%
+65m VHIR
Recovery pH up
Growth + FCR improved
WBC +8%
VO2max; RPE
20 km -4%
Walk +18 m, +22 m
Satellite cells +11
Gait speed +0.4s
Mitochondrial genes up
Aerobic capacity +2.8
Fat burning +12.1%
Bone density +0.020
Fatigue loss −7.1 pp
Collagen damage −38%
Memory + cognition
Recall/recognition gains
Antioxidant/anti-inflammatory recovery
Fatigue/endurance +8.9%
+28W, +1.8min endurance
Maintained sprint power
Endurance +1.4%
Perceived effort -0.8
VO2max +8%
Fatigue/cognition improved
Emotional/autonomic improved
GSH restored, stress↓
Mito function↑
Muscle gain, lower cortisol
Fatigue ↓ early training
LDL, CRP, ET-1 −26–47%
Exercise tolerance improved
Sprint power + work
Fatigue, lactate, noradrenaline
+1.34 kg loss
Energy/sleep up
GI regularity improved
Levodopa exposure/ON +110%
+21.9% ON time
Motor/QoL similar, AEs +18.5%
Heart efficiency +LVEF
Lower fatigue