Proof.Fit

Arginine

19 benefits mapped to clinical evidence across supplements.

Benefit Evidence

NO vasodilation +33%

BP/perfusion changes

ADMA/cGMP shifts

11,502 people

LDL↓, TG−16.6%

Heart injury↓, stays−1d

Vasodilation↑, BP↓

13,023 people

Perfusion+blood flow

Infections/LOS ↓

Collagen+healing ↑

7,930 people

NO vasodilation +blood flow

BP↓; flow↑

+135% arginine, flow↑

6,451 people

AA uptake +35%

Arginine levels rise

Nitrogen balance improves

6,622 people

Perfusion+healing

Infections↓,stay↓

6,671 people

Immune cells↑, infections↓

CRP↓, arginine↑

6,410 people

Infection↓ CRP↓

IL-6/TNF-α↓

SIRS/MOF↓

4,185 people

Metabolism: glucose↓, insulin↑

Metabolism: arginine↓/fat↓

Metabolism: fatty liver↓

2,831 people

Vasodilation, −10 mmHg

Renal flow, −29%

2,998 people

NO/endothelial +, BP −

Muscle/bone/aging +

GH, glucose, mortality

1,368 people

ED scores +5-12

Fertility/pregnancy +47%

Genital blood-flow ↑

976 people

Amino acids ↑; signaling ↑

Recovery strength/endurance ↑

Infections/LOS ↓

930 people
Fertility
Moderate

Semen +47pp; pregnancy +19pp

Oocytes +3.2; fertilization higher

Birthweight +16%; litter +12-19%

1,129 people

Endurance + vasodilation

Power/fatigue +14-35%

528 people

Fatigue/Arginine ↓

Performance/Endurance ↑

348 people
Endurance
Moderate

Endurance capacity +14%

Exercise economy/strain reduced

Walking distance +32 m

321 people

↑ urine flow/sodium

↓ renal blood flow

↓ bowel regularity

421 people

Better focus, faster

Lower stress, steadier

411 people