Proof.Fit

Urolithin A

17 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Healthy aging
Moderate

Muscle/endurance +12%

+urolithin A link

794 people
Energy & Fatigue
Moderate

Endurance up; markers down

VO2max +5.4%

296 people
Metabolism
Moderate

Glucose ↓2 mg/dL

VAT −14.1%

408 people
Inflammation
Moderate

CRP ↓, IL-2 ↓

Acylcarnitines/ceramides ↓, CRP ↓

204 people
Endurance
Moderate

Endurance +muscle

VO2max +5-10%

Walk +33-61 m

196 people
Vitality
Moderate

Endurance +VO2max, +5–10%

Strength/biomarkers +12%; CRP down

196 people
Workout performance
Moderate

Endurance ↑; VO2max +5-10%

Strength/endurance ↑; CRP/acylcarnitines ↓

196 people
Heart health
Weak

Vessel function +1.6%

Lower CVD risk 52%

VAT loss −14.1%

1,466 people
Cell health
Weak

Endurance +60.8m

Strength +12%

154 people
Muscle growth
Weak

Endurance +33.4m

+12% strength

Inflammation ↓

154 people
Strength
Weak

Endurance up +60.8 m

Strength up +12%

Recovery markers down

154 people
Gut health
Weak

Urolithins +100% producers

Butyrate +66%

152 people
Exercise recovery
Weak

Endurance + force, less soreness

Mitochondrial markers, recovery, +5.4% VO2max

108 people
Focus & concentration
Weak

Hippocampal preservation +0.5%

Less ventricular expansion −2.0%

284 people
Memory
Weak

Hippocampal loss reduced −0.5%

Ventricle growth reduced −2.0%

284 people
Immune support
Weak

UroA/butyrate↑ CRP↓

Naive CD8↑ metabolism shift

50 people
Stress resilience
Weak

Gut-metabolic boost; CRP↓

Immune youth shift; IL-2↓

50 people