proof.fit

HMB

13 benefits mapped to clinical evidence across supplements.

Serves the goals:Bone & JointFitnessImmune SupportLongevityWeight Management

Benefit Evidence

Muscle growth
Strong

Lean mass +0.8–12.7%

Muscle loss −2.0 kg

3,008 people
Muscle maintenance
Strong

Lean mass +2.55kg

Muscle loss -14%

3,470 people
Strength
Strong

Strength ↑; +4.6kg grip

Lean mass ↑; +1.2%

Power/function ↑; +21.5% jump

2,100 people
Illness recovery
Strong

Muscle loss↓, strength↑

Mortality↓, recovery↑

Function↑, mass↑

2,501 people
Healthy aging
Strong

Muscle/strength + function

Nutrition/weight + less mortality

Cardio-endothelial +27% FMD

3,204 people
Body composition
Strong

↑Lean mass +3.0kg

↓Fat/VAT −93.8g

↑Strength/power +23%

1,826 people
Exercise recovery
Strong

Damage markers ↓, recovery ↑

Strength/function ↑, stay ↓

1,040 people
Daily comfort
Strong

Strength/mobility +17%

Mass/weight gains

Hospital stay -4.3d

1,763 people
Joint mobility
Moderate

Strength/mobility +17%

Walk +47.6m

550 people
Workout performance
Moderate

Strength/power +18%

Aerobic/endurance +9%

Recovery/damage markers

211 people
Endurance
Moderate

Endurance: +VO2max

Threshold/delay: +9.1% OBLA

Recovery: 24h work capacity

202 people
Muscle soreness
Weak

Less CK, soreness

Better strength recovery

69 people
Bone health
Weak

Bone density/strength +6-28%

Bone density + strength

30 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Leucine

Shares 10 benefits: body composition, bone health, endurance, exercise recovery

Whey Protein

Shares 8 benefits: body composition, bone health, exercise recovery, muscle growth

Essential Amino Acids

Shares 8 benefits: body composition, endurance, healthy aging, illness recovery

Branched-Chain Amino Acids

Shares 8 benefits: body composition, endurance, exercise recovery, muscle growth

Creatine

Shares 7 benefits: bone health, endurance, exercise recovery, healthy aging

Casein

Shares 7 benefits: body composition, bone health, exercise recovery, healthy aging

Products with HMB

Search all

1 product whose verified label declares HMB — not every bottle that mentions it in a title.

Mightnes

Mightnes GLP-1, GLP-1 Supplement for Women & Men, Natural GLP1 Support

GLP-1 Secretion Plant Enhancer Blend 400 mg ¡ Berberine, Green Tea Extract (Camellia sinensis, Leat) ¡ Hops Extract (Humulus lupulus, Flower) +14 more

$19.90Probiotics

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.

Impact of HMB Supplementation on Inflammation and Outcomes in Head and Neck CancerHMB ¡ Head and Neck Cancers ¡ 66 participants planned ¡ ClinicalTrials.govRecruitingTCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone StatusHMB ¡ Pre-Frailty, Sarcopenia, Muscle Atrophy or Weakness ¡ 90 participants planned ¡ ClinicalTrials.govRecruitingThis Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.HMB ¡ Muscle, Cognitive Functioning, Geriatric ¡ 120 participants planned ¡ ClinicalTrials.govRecruiting