Cholesterol
65 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
TG↓
LDL↑
LDL/TC down
~10-15%
Viscous fiber lowers LDL
TG↓, LDL↑
O3I↑, TG↓
HDL↑, LDL↑
LDL↓ HDL↑
TG↓ +39%
LDL/TC -10%
Triglycerides/ratios -13%
Phytosterols up, vitamins normal
LDL/TC down
HDL/TG improved
Ratios improved
LDL ↓20-35%
Total cholesterol ↓13-25%
LDL/TC down
HDL slightly up
LDL/TC ↓ 10–20%
HDL ↑ 0.15 mmol/L
TG ↓, ratios improved
LDL/TC ↓ ~20%
HDL ↑ ~10-30%
LDL/TC ↓ ~5–23%
Absorption markers ↑/↓
LDL -5–30%
Total cholesterol -3–10%
HDL/TG mixed
LDL-C ↑; betaine varies
Homocysteine ↓; betaine ↑
LDL/TC −
TG/HDL +
LDL/TC ↓
HDL ↑
LDL↓ HDL↑
Cholesterol removal↑
HDL/efflux ↑
LDL/TG ↓
LDL↓ 8–16%
Total cholesterol↓ 3–12%
LDL/TC down
HDL up
LDL/TG down
LDL -30%
TC/HDL -21%
LDL/TC ↓
-6.9% LDL
LDL/TC ↓ ~20%
Triglycerides ↓
TC, LDL ↓
TG, HDL ↑
LDL/TC ↓12-15%
Triglycerides ↓23%
LDL/TC ↓
HDL ↑
Cholesterol/TG ↓
Oxysterols/LDL ↓
LDL/TC down
TG down, HDL up
TC/LDL ↓ (−22%)
HDL ↑
LDL/TCHO ↓; +25
Cholesterol synthesis ↓26%
LDL/TCHO ↓
LDL, TC ↓
~7-32%
TG ↓
LDL -10 to -19%
Total cholesterol -6 to -8%
HDL +29%
LDL down ~32%
Total cholesterol down
LDL/TC down 2-7%
Triglycerides down, LDL/TC
LDL/TC ↓
TG ↓ 0.42
HDL↑; ApoB↓
LDL↓ ~9-12%
HDL +4.4; ApoB↓
LDL −17%; TC↓
LDL↓10% absorption
HDL↑66–144%
LDL-C ↓, TC ↓
TG ↓, HDL-C ↑
LDL -22%
TG -37 mg/dL
Akkermansia, LDL-C -9.1%
LPS, small LDL
LDL down, HDL up
VLDL-TG down, small-HDL-TG down
LDL -15.8%, Total -9.7%
TG/VLDL down
Lipids improved
LDL -0.19 mmol/L
Total cholesterol -0.32 mmol/L
LDL/total TC ↓
Non-HDL/TG ↓10-13%
LDL/TC down -21.9%
HDL up, LDL down
Glucose/HbA1c down
LDL/TC/TG ↓
HDL ↑, ApoB ↓
Cholesterol ↓
LDL ↓23%
Lower TC/LDL −25%
Lower TG/non-HDL −15%
Triglycerides −20%
LDL/non-HDL −12 mg/dL
LDL/TC down ~6-11%
ApoB down ~5%
LDL/TC −18%
TG −145 mg/dL
LDL, TG ↓
Non-HDL-C ratios ↓
HDL +11–23 mg/dl
Cholesterol ↓ (lipids)
Total cholesterol −5%
LDL-lowering, modest
HDL +7%
Triglycerides down
EPA/DHA up
TG −22%
LDL ↓4% HDL ↑7%
LDL/TC down, HDL up
Body fat reduction
TG ↓ -14 mg/dL
VLDL ↓ -0.1 mM
↓TC, LDL, TG
↑HDL; BMI/BP↓
LDL −8.1%; total −5.5%
White rice no change
Energy use ↑18.6%
Visceral fat/weight ↓
LDL↓ (significant)
Triglycerides↓ 17-24%
LDL -11.84, TC -16.37
HDL +2.52, TG -16.22
LDL/total cholesterol -5%/-10%
HDL increased
HDL +0.15 mmol/L
Cholesterol up