Hesperidin

16 benefits mapped to clinical evidence across supplements.

Serves the goals:Bone & Joint Cardiovascular Cognition Detox Energy

Benefit Evidence

Vascular health

Strong

Venous tone/flow ↑

Edema/symptoms ↓

2,229 people

Blood circulation

Moderate

BP↓, blood flow↑

vein tone↓, +2.5mmHg

endothelial function↑, inflammation↓

1,470 people

Tissue repair

Moderate

Tissue repair: +5.5% retention

Tissue repair: faster healing/bleeding −5.2%

1,119 people

Inflammation

Moderate

Inflammation genes −3,422

CRP/IL‑6/TNF‑α ↓

Adhesion markers ↓

681 people

Antioxidant

Moderate

Antioxidant capacity ↑

+13% TAC

Oxidative damage ↓

1,098 people

Cholesterol

Moderate

TC/LDL ↓ (−22%)

HDL ↑

559 people

Cell health

Moderate

Metabolic-oxidative: MGO↓37%

Liver-glucose: enzymes/steatosis↓

448 people

Immune support

Moderate

Inflammation genes ↓

Glucose/IL-6 ↓

1,560 people

Blood pressure

Moderate

SBP −5–7 mmHg

DBP lowered

480 people

Healthy aging

Moderate

Cognition + attention

Glucose/inflammation −6% to −49%

248 people

Exercise recovery

Moderate

Aerobic recovery +8.9W

Sprint recovery −5.7%

242 people

Blood sugar

Moderate

↓ FPG/HbA1c

↓ HOMA-IR / MG

381 people

Energy & Fatigue

Moderate

Power/energy: +17.7%, +8.9 W

Soreness/damage: CPK −32.6

212 people

Brain health

Weak

Cognition + attention

Fall risk -

MDA -14%

109 people

Gut health

Weak

Gut absorption ↓29.7→9.3 μmol

Stool phytochemicals ↑37-fold

849 people

Allergy relief

Weak

CRP histamine IL-1 -28%

Inflammation reduction -45% histamine

60 people

Main Effects

Vascular health

Venous tone/flow ↑

Edema/symptoms ↓

Strong

2,229

Blood circulation

BP↓, blood flow↑

vein tone↓, +2.5mmHg

endothelial function↑, inflammation↓

Moderate

1,470

Tissue repair

Tissue repair: +5.5% retention

Tissue repair: faster healing/bleeding −5.2%

Moderate

1,119

Inflammation

Inflammation genes −3,422

CRP/IL‑6/TNF‑α ↓

Adhesion markers ↓

Moderate

681

Antioxidant

Antioxidant capacity ↑

+13% TAC

Oxidative damage ↓

Moderate

1,098

Cholesterol

TC/LDL ↓ (−22%)

HDL ↑

Moderate

559

Cell health

Metabolic-oxidative: MGO↓37%

Liver-glucose: enzymes/steatosis↓

Moderate

448

Immune support

Inflammation genes ↓

Glucose/IL-6 ↓

Moderate

1,560

Blood pressure

SBP −5–7 mmHg

DBP lowered

Moderate

480

Healthy aging

Cognition + attention

Glucose/inflammation −6% to −49%

Moderate

248

Exercise recovery

Aerobic recovery +8.9W

Sprint recovery −5.7%

Moderate

242

Blood sugar

↓ FPG/HbA1c

↓ HOMA-IR / MG

Moderate

381

Energy & Fatigue

Power/energy: +17.7%, +8.9 W

Soreness/damage: CPK −32.6

Moderate

212

Brain health

Cognition + attention

Fall risk -

MDA -14%

Weak

109

Gut health

Gut absorption ↓29.7→9.3 μmol

Stool phytochemicals ↑37-fold

Weak

849

Allergy relief

CRP histamine IL-1 -28%

Inflammation reduction -45% histamine

Weak

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Resveratrol

Shares 11 benefits: antioxidant, blood circulation, blood sugar, brain health

Epigallocatechin Gallate

Shares 11 benefits: antioxidant, blood circulation, blood sugar, brain health

Anthocyanins

Shares 10 benefits: antioxidant, blood circulation, blood sugar, cell health

Quercetin

Shares 10 benefits: allergy relief, antioxidant, blood circulation, blood sugar

Berberine

Shares 9 benefits: blood pressure, blood sugar, cell health, cholesterol

Pine Bark Extract

Shares 9 benefits: allergy relief, antioxidant, blood circulation, blood pressure

Products with Hesperidin

Search all

26 products whose verified label declares Hesperidin — not every bottle that mentions it in a title.

ANDREW LESSMAN

ANDREW LESSMAN ProCaps Circulation & Vein Support 60 Capsules

Vitamin C (as calcium ascorbate/palmitate) 30 mg · Diosmin 600 mg · Butcher's Broom, extract (rhizome/root) 80 mg +5 more

$27.90Blended Vitamin & Mineral Supplements

ANDREW LESSMAN

ANDREW LESSMAN ProCaps Circulation & Vein Support 360 Capsules

Vitamin C (as calcium ascorbate/palmitate) 30 mg · Diosmin 600 mg · Butcher's Broom, extract (rhizome/root) 80 mg +9 more

$109.90Blended Vitamin & Mineral Supplements

Hepaclear

Hepaclear Liver Support Supplement with Hesperidin, Vegan, Gluten-Free

Choline (as choline bitartrate) 4 mg · Hepaclear® Proprietary Blend 340 mg · Milk Thistle 80% Extract (80% silymarin) +3 more

$39.95Milk Thistle

Irwin Naturals

Irwin Naturals Immuno-Shield All Season Immune Support

Vitamin C 400 mg · Vitamin E 27 mg · Zinc 9 mg +13 more

$37.98Blended Vitamin & Mineral Supplements

Solgar

Ultimate B+C Complex Stress Formula 90 Tablets

Vitamin C 1000 mg · Thiamine 50 mg · Riboflavin 50 mg +15 more

$20.24Blended Vitamin & Mineral Supplements

KAL

KAL Enhanced Energy Teen Multivitamin Tablets, 60 Tablets

Vitamin A 1500 mg · Vitamin C 200 mg · Vitamin D 25 mcg +86 more

$20.55Multivitamins

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.

Cognitive Effects of Hesperidin in Overweight/Obese Older AdultsHesperidin · Cognitive Dysfunction, Overweight and Obesity · 105 participants planned · ClinicalTrials.govRecruiting Hesperidin RCT in MSHesperidin · Multiple Sclerosis · 60 participants planned · ClinicalTrials.govRecruiting Dose-Response Impact of Glucosyl-Hesperidin (CitraPeak) on Exercise Performance, Blood Flow, Stress, Cognition, and Other Perceptual IndicatorsHesperidin · Exercise Performance, Exercise Recovery, Cognitive Function · 60 participants planned · ClinicalTrials.govRecruiting