Proof.Fit

Nattokinase

5 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Main Effects
Blood circulation

Anticoagulation up; clotting times

+SBP/DBP down; D-dimer up

Moderate
451
Heart health

Clotting slowed; PT/aPTT↑

BP lowered; renin↓ (-5.6/-2.8)

Weak
186
Cholesterol

Lower TC/LDL βˆ’25%

Lower TG/non-HDL βˆ’15%

Weak
160
Blood pressure

SBP βˆ’5.6, DBP βˆ’2.8

Renin activity ↓1.17

Weak
86
Vascular health

BP reduced βˆ’5.55/βˆ’2.84

Renin activity lowered βˆ’1.17

Weak
86