Detoxification

Kaliuresis↑, K+↓

HyperK↓, proteinuria↓

GSH↑, toxicity↓

Detox enzymes↑, exposure↓

Absorption −81% / −99%

Elimination faster +84% removed

Liver detox +survival

Kidney protection -CIN

Absorption block -99%

Elimination boost +53%

Arsenic detox: +DMAs -InAs

Homocysteine detox: -30%

Liver enzymes: -0.6 IU/L

Enzyme↓, ammonia↓

GSH↑, detox↓

GSH/Cysteine detoxification

Homocysteine lowering

Butyrate↑, endotoxin↓

Stool frequency↑, LPS↓

Proteinuria ↓

Renal injury ↓

Inflammation/oxidation ↓

GSH/antioxidant ↑

Detox markers ↓

Ammonia↓, cognition↑

Recovery↑, mortality↓

GPx↑, MDA↓

Toxic metals excretion↑

Mortality 89%→0%

Bulk + frequency

Transit -55%

Constipation symptoms + glucose/lipids

Betaine lowers Hcy

Betaine boosts methylation

Glutathione ↑; MDA ↓

SAM/SAH ↑; tHcy ↔

Infection clearance +60%

Microbial burden ↓

Fibrosis↓, enzymes↓

Kidney function↑, stress↓

Detox enzyme suppression

+80% metabolite reduction

Oxidative stress ↓

Liver/kidney markers ↓

Iron overload ↓

Pollutant detox +60%

Oxidative stress −18%

GGT/ALT ↓

Lead −79 μg/L

Folate +10.2%

Detox markers ↓

Inflammation/oxidation ↓

Choline→TMAO shift

−30% choline, +484% TMAO

Choline/PC detox handling

Liver markers improved

Arsenic detoxification +47.1%

Autophagy/BDNF +7–13%

Detox markers −21–27%

ALT/AST ↓

Paraquat clearance ↑

Toxin rise prevented

Estrogen metabolism +3.2

Tamoxifen metabolites ↓

CIN regression; 50%

Detoxification: ↓ oxidative stress

Detoxification: ↑ antioxidant defenses

Liver detox +10

Metabolic detox markers

ALT/AST ↓

Liver fat −11%

Lower IL-6, IL-1β

GCF antioxidants +TAOC

Liver enzymes normalise

Ferritin/AKI reduced

CYP3A/CYP2C19 ↑

CYP1A2 ↓

ARM clearance ↑4x

↓ Genotoxicity

↑ Bile acid/SCFA excretion

GSH/vitamins +40%

Neopterin -30%

Acrylamide excretion ↑

Copper absorption↓ 82%

Ceruloplasmin↓, neurologic risk↓22pp

Kidney stabilization, IL-6↓

CRP/IL-6↓, creatinine clearance stable

ALT/AST, fibrosis markers ↓

BaP/cotinine ↑, glucose ↓

Bilirubin ↓, phototherapy ↓

Rash/bowel ↑

Lower toxic enzymes/bile acids

Symptom reduction -48%/-64%

BP, NO

Bile acids, cholesterol

Aflatoxin adducts −55%

Fecal mutagenicity −28%

Liver enzymes ↓

Albumin ↑, fibrosis ↔

Bile UDCA ↑

ALDH +18.1%

Breath alcohol −59%

Beers −1.1

Phosphorus -0.7 to -1.0

Albumin improved

TMAO/DMA ↓; ~39%

Metabotype-specific detoxification ↓

Thiamine status ↑

ETK activity ↑

UAE −18 mg

↑ urine output, clearance

diuretic renal effect

Liver enzymes −44%

Oxidative stress, ferritin

Cesium burden -62.6%

Detoxification lowered 11.3 Bq/kg

Plaque/gingiva improvement

Bleeding reduction

↓γ-GT, MDA; ↑SOD

Antioxidant detox boost

JAK/STAT suppression

Autophagy ↓