TUDCA

Neuroprotection, less inflammation

ALS decline slowed +0.42/month

Survival +6.5 months

Reduced damage/inflammation

Slowed decline,+6.5mo

Slower ALS decline +0.42/mo

Longer survival +6.5 mo

Liver enzymes down

ALP/symptoms improved

Albumin up

↓ inflammatory markers

immune shift

Antioxidant enzymes +

Oxidative stress -

MDA -

Liver enzymes ↓

Albumin ↑, fibrosis ↔

Bile UDCA ↑

GBEF +13.3%

Symptoms -3.8

Immune cells shifted +

Bile acids increased