Stress resilience
59 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
Exercise/time: +5-230%
Cardio-kidney protection: -21% CIN
Stress/anxiety ↓
Cortisol ↓
Sleep/function ↑
Stress proteins/immune +HSP70
Injury/infection markers −~30%
Metabolic support, survival +26.7pp
Stress resilience: ↓ cortisol/anxiety
Stress resilience: ↑ mood/sleep
Stress: ↓cortisol, -1.8 cm waist
Stress: mood/energy ↑
Stress: inflammation ↓
Immune/infection ↓
Glucose/stress ↓
Depression scores −11 to −15
Side effects fewer than drugs
Relapse reduced; response +20%
↓NE, stress
↓anxiety/cortisol
↑HRV, ↓MAP
Stress/anxiety ↓
QoL/alertness ↑
Catecholamine depletion: stress↓ resilience
Tyrosine/L-DOPA: stress↑ resilience
+16% vasoconstriction
Lower stress +25%
Better stress resilience
Anxiety/stress ↓
Craving/withdrawal ↓
Lower anxiety/stress markers
Reduced stress response
Stress/anxiety ↓
-3 points
Pain/opioid -50–80%
Fear extinction improved
DHEA↑, cortisol↓
-38% cortisol
Immune boost, stress protection
Less illness, shorter duration
Less stress, more energy
↓IL-6/MDA; ↓mortality
Cardio stress -?
Stress/anxiety −3
Fatigue/attention +14.8%
Cortisol block: +4.9 ng/mL
DCS anxiolysis: 71% vs 25%
BP/Cortisol stress
Anxiety/Mood stress
Heart function +7–8%
Stress/inflammation protection
Energy biomarkers −
Stress resilience +faster symptom relief
Stress resilience -inflammation -11.5
Lower cortisol/ACTH
Stress response ↓
Blunted cortisol +4.87
↓ recall, ↑ anxiety
↑ mood, ↓ anxiety
↑ stress hormones, flux
Stress/anxiety ↓
Cortisol ↓
Mood/sleep ↑
↓ physiological stress
↓ anxiety/stress -17 to 22
↓ cortisol/HRV response
Oxidative stress, BP ↓
Immune recovery, TNF ↓
Anxiety/stress ↓
Sleep/anxiety ↓
Nutrition↑, +127g
Wound healing↑, -16d
Reduced panic/depression
Stress scores improved
Stress resilience: HRV/BP +14%
Stress resilience: fetal cortisol -33%
Stress resilience +PSS -5.9
BP stress reactions improved
CD4/IFN-γ boost
+2.35 GAD-7
Endurance +21–25%, HR↓
Fluid retention/plasma volume↑
Time-to-exhaustion, mass loss↓
Burnout, mood better
+ stress BP/HR response
Stress resilience +10–24%
Mood/cognition benefit
Stress↓ sleep↓
Dialysis↓ −18%
Less withdrawal, pain
Mood/cognition boost
PANSS/SANS better
HAM-D/remission better
Stress↓ collagen↑ 0.35
Metabolites shift; stress↓
Gut inflammation ↓
Lead uptake ↓ 86-90%
Anxiety -22%
Cardio stress response
Stress system optimized
Stress resistance improved
KCCQ +26, EF +8%
BNP −72, ATP balance
Fewer severe side effects
QOL recovery, +6 months
Stress resilience: cortisol -
Stress resilience: anxiety/HR -8.1
Stress resilience: glucose/redox +10%
Hot flashes -69%
Menopausal symptoms down
Depression symptoms -6%
Response rates +23%
Lower inflammation markers (-34%)
Reduced stress load (-20%)
Decision speed +8.5%
HRV stability, delayed decrease
Gut-metabolic boost; CRP↓
Immune youth shift; IL-2↓
Stress -4.3
Sleepiness -1.2
Startle reactivity ↓
30–60 min, no HR/BP
Activity/mobility +
Pain/recovery -
CV recovery, stress tolerance
+diastolic BP only
Anxiety, mood, sleep
+27 min sleep
Stress↓ energy/sleep↑
GI regularity↑
Mood maintained; fatigue ↓
Inflammation markers ↓; BDNF ↓