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L-Proline

13 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Collagen synthesis +55%

Wound healing +61%

3,551 people
Bone health
Moderate

CTX -37%; BMD +1.6%

ALP/Hydroxyproline ↓

BMD loss ↓35-43%

1,109 people
Skin repair
Moderate

Collagen synthesis +55%

Wound healing faster

402 people

Collagen synthesis +100%

OA pain/function ~50%

751 people

Proline/arginine ↑; immunity +

Antibodies ↑; inflammation ↓

375 people
Strength
Moderate

Collagen synthesis +100%

Wound healing, +20%

Bone turnover, -45%

325 people
Gut health
Moderate

Mucositis/reflux ↓

Constipation: stool ↑

315 people

Collagen synth. +PINP

Skin roughness -16%

Wrinkles improved 58%

206 people

Recovery: collagen synthesis + proline

Protein sparing: +130 mg/kg

160 people

Stress↓ collagen↑ 0.35

Metabolites shift; stress↓

104 people

MPS ↑ proline

Collagen synthesis ↑ proline

69 people

Collagen synthesis +dose

Wrinkles/roughness improved

126 people

Brittleness āˆ’16%/āˆ’19%

Silicon uptake

50 people

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with L-Proline

Search all

54 products whose verified label declares L-Proline — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.