47 supplements analyzed and ranked by clinical evidence.
Autonomic/stress ↓; catecholamines
Seizures/neurology ↓; +40%
ON/OFF time +1.4h
Motor scores -1.9
Tremor -70%
Falls/balance improved
Neuropathy risk lower
Hypocalcemia, QTc +0.03s
GABA release, calcium-dependent
Symptom relief, +33% nerve
Nerve function, B12↑ homocysteine↓
K+ loss, ECG changes
RBC oxidative damage, indices
Nerve symptoms -3.9
Conduction +3.8 m/s
Pain -33%
Nerve symptoms, homocysteine
+30% homocysteine drop
Nerve conduction improves
vasospasm/infarction ↓
brain/vision development ↑
AA/DHA blood ↑
Choline boost, memory +25%
Visual/brain function, IOP -7 mmHg
Cognitive/neurologic improvement
Nerve protection, -2.65 TSS
Neuropathy symptoms/pain
Stroke/ischemia recovery
Migraine days -44%
Smell recovery: 18→7 days
Bad breath: VSC ↓
Neuropathy symptoms↓
Movement/tremor relief
Pain/symptoms ↓
Nerve sensation ↑
Neuropathy score ↓
Pain ↓ ~4
Depression ↓ ~11
Pain/sensory relief
+30 µg/L thiamine
Nerve function improved
Nerve recovery +7.0 m/s
Pain relief -39%
Functional improvement +6.0
Nerve function +
Neuropathy symptoms -0.92
Neurological recovery +25%
Nerve protection: +6.5 mo
Excitability/arousal: threshold↑, ASI↓
EEG preserved +0.015
Nerve symptoms improved
Conduction improved, unspecified
Pain relief / sleep
Seizures / cognition
Cognitive decline ↓
Behavioral symptoms ↓
Dementia conversion ↓8.2%
Anxiety ↓; HAM-A −3.2
Well-being ↑; BP/HR ↓
Nerve pain/recovery
Better by +3
Functional/neurologic gains
Dizziness/vertigo relief -67.7%
Better function/QoL +15%
Improved gait +7 steps/min
CIPN reduced: 1.6 vs 2.3
Motor function worsened
Pain +
Nerve conduction +≈33%
Inflammation down, cytokines↓
Auditory plasticity, MMN
+10% learning
β-ERD, alpha/MMN
Cognition/attention + faster RT
Eye-motor/sensorimotor gating +PPI
Slower ALS decline +0.42/mo
Longer survival +6.5 mo
Neuropathy: -1.5 score
1-deoxySL: -41% / -60%
Pain: -43% worst pain
Lower brain copper exposure
Less neurologic worsening
Improved cognition
Disability & relapse ↓
Pain & symptoms ↓
Membrane synthesis +7.3%
Visual/EEG gating improvement
Biotin: enzyme support
MS: slower disability
+25% mortality reduction
Basophil loss; CCL2 +457%
Bowel movement faster; MTL/5-HT ↑
Inositol: +70% CSF
Neuropathy relief: +64%
Anxiety -10
Alertness/fatigue
Nerve safety
Pain, swelling: -3.8/-21.8
Pain relief: +94.44%
Sleep, mood, anxiety improved
No % change reported
E. coli UTI recurrences ↓
Recurrence-free time +14 days
Pain −26.7%
Axon damage, edema
Learning/memory ↑
Neurogenesis ↑
Less neurologic decline (-22%)
Better recovery
BDNF, NAA +8.6%
Orientation +22.2%
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