Proof.Fit

Eye health

47 supplements analyzed and ranked by clinical evidence.

Supplements47

Supplement Evidence

Main Effects
Vitamin A

Dark vision +11.8%

Vitamin A status↑

Strong
130714
Omega-3 Fatty Acids

AMD risk ↓

Dry eye/vision ↑

Strong
288519
Fish Oil

Visual acuity + retinal function

ROP risk -16%

Strong
290520
Docosahexaenoic Acid

AMD risk ↓

Visual acuity ↑

Strong
140520
Lutein

Macular pigment + vision

AMD risk ↓ ~9%

Strong
2588
Beta-Carotene

AMD risk ↓

Vitamin A status ↑

Strong
80713
Riboflavin

Keratoconus flattening +1.5 D

Cataract reduction βˆ’43%

Strong
32415
Hyaluronic Acid

Staining/symptoms -3 pts

Tear stability/production +2s

Corneal healing +

Strong
131813
Zeaxanthin

AMD progression: -10%

Retinal pigment/function: +MPOD

Strong
1567
Vitamin B2

Kmax flattening + vision

cataract risk βˆ’44%

Strong
40015
Vitamin E

AMD slower +25%

Cataracts/retina improved

Strong
181517
Zinc

AMD progression -25%

Vision loss / function

Macular electrophysiology +38%

Strong
180417
Arachidonic Acid

Eye health: better vision

ROP ↓ 16-17%

Strong
59519
Multivitamin

Nuclear cataract βˆ’34–44%

PSC cataract +100%

Cataract risk βˆ’13%

Strong
45018
Citicoline

Improved acuity, +92%

Slower field loss, -0.95 dB/year

Moderate
7614
Vitamin B6

AMD risk ↓34%

Cataract odds ↓

Moderate
54417
Anthocyanins

Dry eye symptoms/tear stability +11.35

Glaucoma/night vision/IOP

Retinal protection/visual recovery

Moderate
13119
Coenzyme Q10

Vision/color gains

Retina/nerve stability

Moderate
34817
Phosphatidylcholine

Visual function + stabilisation

Lutein/zeaxanthin +

Moderate
29617
Alpha-Linolenic Acid

Better visual acuity

Rod function preserved

Moderate
31119
Ginkgo Biloba

Vision/blood flow +23%

Glaucoma/DR risk -15.5%

Moderate
22317
Glutathione

Oxidative stress ↓

Corneal protection ↑

Moderate
124419
Alpha-Lipoic Acid

Near vision +37%

Contrast sensitivity / ERG

Corneal pain, nerves

Moderate
21217
Saffron

Vision/function +0.69 letters

Retinal function/IOP -3.25 mmHg

Moderate
10718
Carnosine

Vision + glare better

IOP - improved retina

Moderate
7717
Goji Berry

Macular pigment +

Moderate
1917
Bilberry

Retina function +38%, +30%

Eye fatigue, near vision

Moderate
278
Pine Bark Extract

Retinal swelling/leakage -15ΞΌm

+10 cm/s flow

Allergy eye symptoms -35%

Moderate
5318
Taurine

Slowed field loss

Dry eye improved

Moderate
24013
Black Currant

IOP ↓, field loss ↓

Blood flow ↑, ET-1 normalized

Moderate
5113
Flaxseed Oil

Symptoms, tear stability

Staining, +36% ratio

Moderate
11617
Astaxanthin

Retinal function + blood flow

Visual acuity + fatigue

Moderate
5617
Sea Buckthorn

Dry-eye symptoms improved

Tear osmolarity reduced

Moderate
217
Idebenone

Visual acuity +0.1 logMAR

Colour contrast +13.6%

RNFL preserved

Moderate
2411
Avocado

Lutein/MPD +25%

β-carotene→A+12.6x

Moderate
4716
N-Acetyl Cysteine

Tear stability/immunity +23%

Corneal rescue +21.7%

Weak
62317
Thiamine

GA risk ↓

Dry-eye signs/symptoms ↑

Weak
20515
Beef Liver

Retinol↓, backfat↑

Ξ²-carotene↑, backfat↓

Weak
4511
Rutin

Macular function +38%

+30%; dry eye

Vision, edema improved

Weak
8613
Danshen

FFA, Fundoscopy +46-49pp

Fundoscopy +31-48pp

Weak
12117
Lycopene

Carotenoids ↑; inflammation ↓

Retinal sensitivity +2.0

Weak
19618
Vitamin B1

Corneal nerves + symptoms

Nerve length/width ↑

Neuromas ↓, OSDI ↓

Weak
26717
Grape Seed Extract

Hard exudates improved +35.9%

Macular thickness/volume decreased

Weak
4413
Evening Primrose Oil

Dryness/comfort improved

Tear meniscus height increased

Weak
4810
Quercetin

Eye symptoms ↓; -62.5%

Itching/congestion ↓; quercetin ↑

Weak
14219
Krill Oil

Tear stability βˆ’19.8

Symptoms/IL-17A βˆ’18.6

Tear osmolarity βˆ’18.6

Weak
3815
Resveratrol

Choroidal thickness +16.8ΞΌm

Possible choroidal vasodilation

Weak
17619