Proof.Fit

Skin repair

50 supplements analyzed and ranked by clinical evidence.

Supplements50

Supplement Evidence

Main Effects
Collagen

Healing rate +56%

Scar control +32pp

Collagen synthesis +69x

Strong
295114
Hyaluronic Acid

Healing faster +7.6d

Adhesions lower +23%

Collagen/wrinkles +12%

Strong
131813
Arginine

Perfusion+healing

Infections↓,stay↓

Strong
125319
Silica

MTA: repair +95%

Ca-silicate: bridge/healing

Strong
79615
Zinc

Ulcer healing +90%

Mucositis pain reduction

Wound infection −79%

Strong
180417
Lysine

Wound healing +34%

Bleeding/pain control

Strong
36818
Chitosan

Repair/healing +fast

Bleeding control -90%

Strong
11618
Vitamin E

Healing faster: -35 days

Less inflammation, more repair

Strong
181517
Vitamin C

Wound healing improved

Pain/inflammation reduced

-6.8 PUSH points

Strong
151318
Boron

Severity↓, clearance↑

Itch↓, flares↓

AE low

Strong
1808
Aloe Vera

Faster healing, less pain

-2.8 days

Less skin breakdown, redness

Strong
11312
Comfrey

Pain/swelling relief

+61.1, faster healing

Strong
115
Vitamin A

Skin repair +28 pp

Healing speed improved

Moderate
130714
Pantothenic Acid

Barrier repair + hydration

Pain/redness reduction + faster healing

Moderate
585
Gotu Kola

Redness/barrier −38%

Scar/wound scores↓

Moderate
3814
DMSO

Healing +21-64%

Necrosis -81%

Moderate
8712
Copper

Infection↓ healing↑

TE +0.63 ICU

Wound closure↑ +44%

Moderate
64718
Propolis

Faster wound closure

Less inflammation

Moderate
9516
Vitamin B5

Barrier repair + hydration

Pain/redness healing +50%

Moderate
708
Manuka Honey

Faster healing, +11%

Less infection, better repair

Moderate
276
Bromelain

Faster debridement, less surgery

Pain ↓, repair ↑

Moderate
4510
L-Proline

Collagen synthesis +55%

Wound healing faster

Moderate
96113
Fumaric Acid

Skin clearance +76%

QoL improved +46%

Lower FAE dose -24%

Moderate
367
Birch Bark

Faster closure, +1 day

Less dysplasia, 64%

Moderate
63
Arachidonic Acid

↓ platelet activation

↑ repair markers

Moderate
59519
Beta-Carotene

Skin repair +23%

Faster wound closure 50%

Moderate
80713
Chamomile

Faster healing, less pain

-6 days healing

Moderate
7817
L-Histidine

Repair ↑ nitrogen +130

Histidine/UV protection improved

Moderate
15916
Alpha-Ketoglutarate

Fast graft closure +31d

Less protein breakdown

Moderate
6910
Alanine

Mucositis ↓14/20

Severity/duration ↓

Infections/complications ↓

Moderate
302818
Pine Bark Extract

Wound healing up

Bleeding/symptoms down

Moderate
5318
Leucine

Protein balance + synthesis

Wound repair + collagen

Moderate
39217
Papain

Skin reactions -10

Mucositis/skin reactions -10

Moderate
283
Grape Seed Extract

Healing time -50%

Periodontal scores improved

Moderate
4413
Myrrh

Pain↓, healing↑

REEDA↑, sensitivity↓

Moderate
279
Calendula

Bacteria ↓, faster repair

Pain/swelling ↓, healing↑

Epithelialization 8.6 vs 13.2d

Moderate
257
Tea Tree Oil

MRSA clearance +41%

Nipple cracks/pain ↓

Skin-site clearance better

Weak
479
Sea Buckthorn

Healing rate +33%

Healing time shorter

Weak
217
Yarrow

Pain/swelling -1.32

Mucositis healing -2.07

Weak
287
Neem

Skin repair pain ↓

Pathology severity ↓ 68%

Weak
1913
Royal Jelly

Ulcers, oxidative stress

Mucositis healing time

Weak
2712
Black Seed Oil

Pain relief, day 2

Lesion shrinkage, ~93%

Weak
4915
Manganese

Downtime/erythema reduced

SOM 1.5d, −22%

Weak
8714
Serrapeptase

Swelling, pain reduction

Mouth opening +4.8mm

Weak
67
Echinacea

Elasticity+collagen, MDA↓

Barrier lipids+eczema↓

Weak
5413
Mullein

Wound healing: -1.59

Healed by day10: +54.7%

Weak
34
Dragon's Blood

Healing +10%

Pain reduced

Weak
55
Vitamin K

Bruising ↓; healing +

Early bruise relief; +

Wound contraction +10%

Weak
66214
Castor Oil

Less swelling/scabbing

Better epithelialization

Weak
354
Clove

Healing +48%

Pressure lowered

Weak
338