Bromelain

Pain ↓, function

Pain ↓, swelling ↓

Swelling−34.4% / seroma−73.8%

Edema/swelling↓

Pain/swelling↓

Pain/swelling ↓

Healing/debridement ↑

Pain/tenderness ↓, +41%

Stiffness/function improved, ~−3

Faster debridement, less surgery

Pain ↓, repair ↑

Post-op pain/swelling ↓

BOP ↓ 35.7%

Ortho pain ↓

Immune modulation: IFN-γ

Inflammation relief: −3.29 SCCAI

Vessel function, BP

Oxygenation, circulation

Bronchitis severity/cough +14%

Cough severity/frequency

Disease activity ↓3.29

Quality of life similar