Appetite suppression
38 supplements analyzed and ranked by clinical evidence.
Supplement Evidence
Satiety/intake ↓
Glucose/hormones ↓
Weight ↓
Ephedrine: -2.2kg + app.
LDX/PHEN: appetite -3.1%
Nicotine ↓ hunger; +1.7 kg
Nicotine gum/patch ↓ weight
Whey/AA ↑ satiety hormones
Trp/Phe ↓ intake 10-20%
GLP-1↑ hunger↓
Amino acids↔ satiety↑
Insulin/gastric emptying↓ appetite↓
Satiety +19% intake↓
Hunger/fullness improved
Energy intake −18%
Delayed emptying +80.9%
More weight loss +3.4 kg
Improved satiety
Satiety hormones ↓ intake
5‑HTP/Trp suppress appetite
HP breakfast, −20% ghrelin
High protein, fuller, less hunger
Beef/protein, slight satiety gain
Satiety hormones up
Ghrelin down, intake ↓
CCK/GLP-1 boost
Appetite ↓, +SQ
Cravings/Binge ↓
CCK/GLP-1 ↑ satiety
Intake ↓ 44 kcal
DMI/satiety ↑ ~7%
Hunger/cravings ↓
Glucose control ↑
Hunger↓; no intake
GLP-1/PYY↑; hunger↓
Satiety↑; hunger↓
Satiety/fullness +10%
Hunger/intake -257 kcal/day
satiety ↑, intake ↓
reward response ↓
Appetite↓, CR 77%
Appetite↓, hunger↓
Appetite↓, score↓
More weight loss, less regain
Hormone shifts, −3.6kg, −5cm
Modest fat loss, −2.8lb
Lower hunger, −17% intake
More fullness, +17.2 score
Akkermansia/OEA: appetite -
OEA yogurt: appetite -
L‑Phe ↓ intake ~31%
Whey/Phe ↑ satiety; ↓ hunger
Sweet desire -42%
Pleasantness/liking ↓
Chocolate intake -0.5 bar
Leucine/AA ↑ satiety, CCK
Whey/BCAA ~13% intake ↓
Hunger ↓; fullness ↑
Appetite score +17.2
Satiety ↑; intake ↓
Fullness ↑; hunger ↓
Hunger ↓, waist −2.7cm
Calories ↓229 kcal/day
Slower emptying, more satiety
−112 kcal intake
Delayed emptying, −16% intake
Boosted satiety, −5.1 kg
GLP-1 ↑, DPP-4 ↓
Weight −4.7 kg
CLA: IL-1β↓, appetite↑
CLA: satiety↑, intake↓
Weight loss, snacking ↓
Greater weight loss; fewer snacks
Hunger↓ Satiety↑
Snack intake↓
↓ hunger, PFC
no intake/weight change
Fullness ↑
Blood glucose/BMI ↓
Fullness, -17% fat
Lower lunch intake
Lower hunger, −488 kJ
Blunted glucose spikes, ~−73%
↑ hunger, ↓ satiety
↓ pressure, ↓ appetite
Satiety +23%
Insulin -37%
PYY +2.5x