proof.fit

Learning

21 supplements analyzed and ranked by clinical evidence.

Supplements21

Supplement Evidence

Choline
Strong

Memory + learning

Attention + processing

762 studies·18 benefits
Nicotine
Strong

Memory/attention +

Reaction time -

2862 studies·15 benefits
L-Tyrosine
Strong

Learning ↑, depletion ↓

Dopamine precursor shifts

+38% variance, improved learning

3252 studies·11 benefits
Galantamine
Moderate

Thinking +3.6

Daily function +3.4

110 studies·10 benefits
Piracetam
Moderate

Memory +46%

Language/reading gains

155 studies·10 benefits
L-Dopa
Moderate

Motor symptoms +6.4

Cognition/speech fluctuates

ON/OFF −1.5h

606 studies·13 benefits
Citicoline
Moderate

Memory/attention +3.5

Craving/use −6.41x

76 studies·14 benefits
L-Serine
Moderate

Learning+extinction: better

Learning+consolidation: better

737 studies·17 benefits
Oxiracetam
Moderate

Global cognition + memory

Attention + reaction time

MoCA/LOTCA +9

13 studies·9 benefits
Phenylalanine
Moderate

P/T depletion: learning shifts

Levodopa: learning boosts

1103 studies·16 benefits
Huperzine A
Moderate

Memory +11, learning

Cognition +4.6, ADL

Language scores improved

12 studies·9 benefits
D-Serine
Moderate

Mood/attention + memory

Auditory learning +10%

20 studies·10 benefits
Phosphatidylserine
Moderate

Memory tests improved

+1.1 recall

n-3 PUFAs/neurotransmitters up

58 studies·11 benefits
Aniracetam
Moderate

Cognition + MMSE

Memory +79%

Psychobehavioural improvement

7 studies·6 benefits
Bacopa Monnieri
Moderate

Memory + attention

MCI cognition + fluency

Memory speed +10%

13 studies·11 benefits
Sarcosine
Weak

Symptoms + function

+ cognition/function

38 studies·10 benefits
Theanine
Weak

Attention speed/accuracy

+15–20 ms

Distraction/alertness

39 studies·15 benefits
Vinpocetine
Weak

Cognition + function improved

Clinical status, cognition improved

18 studies·8 benefits
Pyritinol
Weak

Cognition, EEG; better

Speech, vocabulary; 3x gains

7 studies·7 benefits
Polygala Tenuifolia
Weak

Better recall, fewer errors

- p<0.05

Improved maze learning

3 studies·8 benefits
Uridine
Weak

EEG network +0.015

+memory, inconsistent

220 studies·6 benefits