32 supplements analyzed and ranked by clinical evidence.
Alertness +, RT↓
Blood pressure +, alertness +
Catecholamine boost
Sleepiness/alertness shift
+52% intubation
Alertness+RT
Craving+HR
Earlier sleep onset + alertness
Sleep quality + sleepiness
Alertness ↑; cognition
Tyrosine depletion ↓ alertness
Alertness ↓, RT slower
Alertness ↑, RT faster
Memory/attention +p<0.05
Fatigue/alertness +MMSE
+ammonia cognition EEG
Less sedation, alertness up
BIS up, alertness lighter
Memory/attention +
Fatigue/cognition +
Attention/working memory +
Fatigue/stress -2.7 to -4.3
Alertness: faster processing
Alertness: improved attention +31ms
Alertness↑ stress
Alertness↑ panic
Alertness/anxiety ↑
Autonomic activation ↑
Panic/startle ↑
Alertness: - first hours
Alertness: no next-day
Attention + cognition
Reaction time +8.97
Memory + alertness
Attention/cognition +0.73 z
EEG vigilance, hypoxia
Alertness/attention +ms
Alertness/stress −tiredness
Alertness/RT −28ms
Improved alertness, cognition
-21→107 ml/min
Attention/RT faster -8.5%
Mental fatigue lower
Attention/RT +p<0.05
Sleepiness −7.1
EEG alpha/theta −15%
Attention/orientation +
EEG arousal shifts
Alertness up: +4.6
+2.7 MMSE
AChE down >50%
Cognition, sleepiness +29%
Memory/fluency preservation
Attention lapses reduced
Memory + stress ↓
Attention/speed/accuracy ↑
Attention/memory +
Relaxed alertness
CGI/SKT improved
Severity decreased
BP +3–5 mmHg
Energy/focus ↑
Speed/attention, alertness +5.9%
CBF/processing speed, DSST improved
Verbal memory +6.3%
Fatigue ↓; alertness ↑
Cognition +0.21
Attention + fast RT
Cognition maintained -2.2
Attention/speed/accuracy improved
Errors trended down
Locomotion/exploration ↑
Sniffing ↓ over time
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